2009, Number 3
<< Back Next >>
Rev Mex Pediatr 2009; 76 (3)
Prognosis value of hypoalbuminemia in critically ill children
Bocanegra-Cedillo IE, Garza AAG, Rodríguez VI, Ábrego MV, Maltos VW
Language: Spanish
References: 15
Page: 117-120
PDF size: 115.03 Kb.
ABSTRACT
Objective. The low concentration of blood albumin was evaluated as a prognosis factor in children critical ill.
Material and methods. The clinical files of 61 critical ill children with albumin levels measured in the first 48 h of admittance were studied for the hypoalbuminemia relationship to other variables related to the children as well as the mortality PRISM value obtain at admittance.
Results. The organic dysfunctions developed by patients and the value of PRISM were more frequently seen in the hypoalbuminemia patients.
Conclusions. The hypoalbuminemia state in the critical patients increases the risk of died and the development of organic dysfunction in critical ill children.
REFERENCES
McPherson RA, Pincus MR. Henry’s clinical diagnosis and management by laboratory methods. 21st ed. Philadelphia, PA: Saunders-Elsevier Science Publishers: 2007.
Durward A. Hypoalbuminemia in critically ill children: incidence, prognosis, and influence on the anion gap. Arch Dis Child 2003; 88(5): 419-22.
Horowitz IN, Kenneth T. Hypoalbuminemia in critically ill children. Arch Pediatr Adolesc Med 2007; 161(11): 1048-52.
Jin Sung et al. Admission serum albumin is predictive of outcome in critically III trauma patients. Am Surg 2004; 70: 1099-102.
Nicholson JP. The role of albumin in critical illness. Br J Anesth 2000; 85: 599-610.
Zimmerman JE. Acute physiology and chronic health evaluation (APACHE) IV: hospital mortality assessment for today’s critically ill patients. Crit Care Med 2006; 34(5): 1297-310.
Martin GS. Pharmacological aspects of albumin as a niche product in the intensive care unit. Crit Care Med 2005; 33(7): 1667-9.
Goldwasser P, Feldman J. Association of serum albumin and mortality risk. J Clin Epidemiol 1997; 50(6): 693-703.
Yap FH, Joynt GM, Buckley TA, Wong EL. Association of serum albumin concentration and mortality risk in critically ill patients. Anaesth Intensive Care 2002; 30(2): 202-7.
Meites S, Buffone GJ, ed. Pediatric Clinical Chemistry (3rd ed.), Washington, D.C.: AACC Press. 1989.
CDC, Percentiles de estatura por edad y peso por edad. http://www.cdc.gov/nchs/data/nhanes/growthcharts/Spanishpdf95/co061021.pdf
Pollack MM, Ruttiman UE, Getson PR. Pediatric risk of mortality (PRISM) score. Crit Care Med 1988; 16(11): 1110-16.
Restrepo MI, Dueñas CC, Gonzáles M, Ortiz RG, Granados M, Álvarez C y cols. Asociación Colombiana de Infectología. Primer Consenso Colombiano en Sepsis. Bogotá. Colombia. 2006. http://www.revistainfectio.org/site/Portals/0/volumen11_1/sepsis.pdf
Brahm G, Brett G, Adrienne R, and the Members of the International Consensus Conference on Pediatric Sepsis. International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 2005; 6(1): 83-4.
Vincent JL, Dubois MJ, Navickis RJ, Wilkes MM. Hypoalbuminemia in acute illness: is there a rationale for intervention? A meta-analysis of cohort studies and controlled trials. Ann Surg 2003; 237(3): 319-34.