medigraphic.com
SPANISH

Anales Médicos de la Asociación Médica del Centro Médico ABC

ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2009, Number 3

<< Back Next >>

An Med Asoc Med Hosp ABC 2009; 54 (3)

Dexmedetomidine as a single agent for preoperative sedoanalgesia in ambulatory ophthalmic surgery under regional anesthesia in the Hospital Regional «General Ignacio Zaragoza»

Ramírez PA, Camacho MJP, Delgado CMM, Ruiz VRE, Ojeda VJF
Full text How to cite this article

Language: Spanish
References: 12
Page: 156-160
PDF size: 52.52 Kb.


Key words:

Dexmedetomidine, sedation, analgesia.

ABSTRACT

One of the main targets of pre-anesthetic medication is to relief anxiety of the patient who will be taken to a surgical procedure. Actually most of ophthalmic surgical procedures are done under sedation and regional or topic anesthesia. One of the drugs that provides ansiolysis is Dexmedetomidine, an alpha 2 agonist–adrenergic, which has not been well studied. in anesthesic management. Publications just include its effects to produce sedation and analgesia for no more than 24 hours on patients in the Intensive Care Unit only. On this study we take advantage of these effects as medication and maintenance anesthesic on patients who were programmed for ambulatory ophthalmic surgery (cataract) under regional anesthesia. Material and methods: We present the experience of an experimental, longitudinal, comparative, prospective, opened study of these surgeries with impregnation of dexmedetomidine to 1 µg/kg and maintenance with 0.3 µg/kg in group A and 0.5 µg/kg in group B at the Regional Hospital «General Ignacio Zaragoza», including two groups of adult patients ASA I, II, III, between 50 and 80 years old, both sex, cardiovascular changes like cardiac rate medium arterial pressure and oxygen saturation, Ramsay sedation Scale, and analogy visual scale, were analyzed during pre, trans and post anesthetic time. Statistical analyze: Chi square, and Mann-Whitney U tests were used. Results: no significative statistical differences were found by this study, except the Ramsay sedation scale that was increased in group B, showing important differences at ending of impregnation and beginning of infusion. Conclusions: This research determined the safety and efficacy of two small-dose infusions of dexmedetomidine on the surgery room as surch as a unique new alternative for ambulatory ophthalmic surgeries under regional anesthesia by evaluating sedation, analgesia, cognition, and cardio respiratory function. We found evidence that sustained our hypothesis and no adverse effects were found.


REFERENCES

  1. Rodríguez LMC. Eficacia de la dexmedetomidina como coadyuvante de la anestesia general para pacientes postoperados de rinoseptumplastia comparada con midazolam. Colima, Col: División de Estudios de Postgrado, Hospital Regional Universitario. 2006.

  2. Ramsay MA. The role of dexmedetomidine. Bariatric Surgery 2006; 25: 51-56.

  3. Virkkilä M, Ali-melkkilä T, Kanto J, Turunen J, Scheinin H. Dexmedetomidine as intramuscular premedication in outpatient cataract surgery. A placebo-controlled dose-rangingstudy. Anaesthesia 1993; 48 (6): 482–487.

  4. Cheung CW, Ying CLA, Chiu WK, Wong GTC et al. A comparison of dexmedetomidine and midazolam for sedation in third molar surgery. Anaesthesia 2007; 62 (11): 1132–1138.

  5. Curtis FG et al. Dexmedetomidina e sufentanyl como analgésicos peroperatorios. Estudio comparativo. Rev Bras Anestesiol 2002; 52: 525-543

  6. Bamgbade OA. (2006) Dexmedetomidine for peri-operative sedation and analgesia in alcohol addiction. Anaesthesia 2006; 61 (3): 299-300.

  7. Mato M, Pérez A, Otero J, Torres LM. Dexmedetomidina, un fármaco prometedor. Rev Esp Anestesiol Reanim 2002; 49: 407-420.

  8. Martínez TR, Zambada C, Álvarez González R, González VM, Yáńez C, Reyes E, Díaz A, Domínguez B. Dexmedetomidina versus midazolam como premedicación para cirugía endoscópica de senos paranasales. Valoración de la estabilidad hemodinámica. An Med Asoc Med Hosp ABC 2004; 49 (4): 184-190.

  9. Duarte J. Dexmedetomidina en bolo único. Rev Med Cri 2003; 3: 21-22.

  10. Tanelli MA. Dexmedetomidina en anestesia general. Anesth Analg 2004; 17-29.

  11. Barash P. Manual de Anestesia Clínica. México: Interamericana-McGraw-Hill; 1993. p. 199-203.

  12. Bachand R et al. Alpha 2 adrenergic agonist to prevent perioperative cardiovascular complications A meta-analysis. Am J Med 2003; 5: 114-119.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

An Med Asoc Med Hosp ABC. 2009;54