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ISSN 0188-2198 (Print)

2010, Number 1

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Rev Mex Cardiol 2010; 21 (1)

Index of resistance to the insulin in obese postmenopausal women with and without dyslipidemia

Maldonado-Villalón JA, Sánchez-Soto T, Ortiz-González MJ, Gómez-Alonso C, Álvarez Aguilar C

Language: Spanish
References: 15
Page: 3-8
PDF size: 138.87 Kb.


ABSTRACT

Introduction: Obesity is the main cause of cardiovascular morbidity and mortality, it is associated with systemic arterial hypertension, insulin resistance, diabetes mellitus type 2 and/or dyslipidemia, propitiating a deterioration in the quality of life. Objective: To determine the index of resistance to the insulin and its relation with normolipidemia and dyslipidemia in obese postmenopausal women. Material and methods: Descriptive, comparative, prospective, transversal study in 119 obese postmenopausal women. Variables analyzed: age, blood pressure, body mass index, abdominal circumference, percentage of corporal fat, basal glucose and insulin, test of tolerance to oral glucose, insulin resistance by Homeostasis Model Assessment of Insulin Resistance (HOMA). Statistical analysis: ANOVA rest, and Chi2 in the SPSS 15.0 program. Results: The normolipidemic patients showed normal levels of blood pressure; in the dyslipidemic patients non atherogenic found systemic arterial hypertension stage 1 and resistance to insulin; the dyslipidemic atherogenic patients presented arterial hypertension stage 3, hyperglycemia, insulin basal and insulin resistance index elevated. Conclusions: The normolipidemic patients do not another cardiovascular risk factor associated to obesity/postmenopause; the patients with dyslipidemia mainly the variety atherogenic reflect an insulin resistance stage, a higher risk of developed diabetes mellitus type 2, systemic arterial hypertension or suffer a coronary event.


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