2009, Number 1-3
Rev Mex Enf Cardiol 2009; 17 (1-3)
Factors that modify the adjusted International index in patients suffering from oral anticoagulation
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ABSTRACTIntroduction: Vitamin K is essential for the liver to produce clotting factors and prevent internal bleeding, in contrast to the role of oral anticoagulants (OAC) which inhibit vitamin K The Adjusted International Index (INR) is a standard that measures the prothrombin time. Objective: To identify factors influencing the determination of INR in patients with OCP. Methodology: This was a descriptive cross-sectional study of a population of N = 13.331 patients in the Anticoagulant Clinic of the Outpatient National Institute of Cardiology Ignacio Chavez (INCICH) in 2008, included patients with altered levels INR and excluded patients with INR of 1.5-4.5 leaving a finite sample of n = 73 patients, divided into two groups: high and low INR. The variables were obtained through direct examination and laboratory results of Hematology. Statistical analysis was performed using Excel 2003 and data were expressed as summary measures. Results: Females prevailed in 51%, in relation to the alteration of INR, 71.2% had a 28.8% increase and decrease, the most common sign was epistaxis 29%. In a 58% increase in INR was by the use of drugs, related to antibiotic use in 20%, in patients with borderline effect 88% reported treatment failure for more than 3 days and 27% by excessive intake of vitamin K in the diet. Conclusion: They manage to identify the factors that modify the INR in patients with OCP, good patient outcomes depend largely of addiction treatment and continuing education to provide the nurse.