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>Journals >Cirujano General >Year 2004, Issue 3

Martínez-Duncker RC
Practical gammagraphic evaluations for the diagnosis and treatment of head and neck diseases
Cir Gen 2004; 26 (3)

Language: Español
References: 31
Page: 192-202
PDF: 4. Kb.

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Objective: To analyze the main gammagraphic techniques used for head and neck diseases.
Setting: Third level health care hospital.
Selection of studies: We reviewed 31 studies published in the biomedical literature related to the subject and chose those up-dated in relation to diagnosis and treatment of the main head and neck diseases.
Results: Among the most frequent head and neck diseases, for which gammagraphic assessments provide relevant clinical information for their diagnosis and/or treatment that will be addressed in this review, are those of the thyroid gland (hyperthyroidism, functional thyroid nodules, non-functional thyroid nodules), malignant lesions such as melanomas, for which locating the sentinel node(s), the salivary glands, and the parathyroid glands is essential for adequate treatment.
Useful guidelines are included for the differential diagnosis of diverse thyroid diseases considering the results obtained by means of gammagraphy and complementary laboratory tests (thyroid profile).
Besides, we analyze the treatment of the hyperfunctional thyroid, the incidence of post I131-treatment hypothyroidism, the rational calculus of I131 –dosage (activity), thyrotoxicosis and the thyroid nodule, as well as calculating the functional thyroid mass and the thyroid up-take and retention of I131.
Conclusion: Gammagraphic evaluation of head and neck diseases is a relevant tool for the surgeon.

Key words: Gammagraphy, nuclear medicine, head and neck.


  1. Ravetto C, Colombo L, Dottorini ME. Usefulness of fine-needle aspiration in the diagnosis of thyroid carcinoma: a retrospective study in 37,895 patients. Cancer 2000; 90: 357-63.

  2. Nódulo tiroideo, 2001. Consenso. Cir Gen 2002; 24: 76-83.

  3. Mazzaferri EL. Management of a solitary thyroid nodule. N Engl J Med 1993; 328: 553-9.

  4. Maddox PR, Wheeler MH. Approach to thyroid nodules. In: Clark OH, Duh QY Textbook of Endocrine Surgery. Philadelphia W.B. Saunders 1997: 69.

  5. Vargas-Domínguez A, Arellano S, Alonso P, Viramontes Madrid JL. Sensibilidad, especificidad y valores predictivos de la biopsia con aguja fina en cáncer de tiroides. Gac Med Mex 1994; 130: 55-8.

  6. Singer PA, Cooper DS, Daniels GH, Ladenson PW, Greenspan FS, Levy EG, et al. Treatment guidelines for patients with thyroid nodules and well-differentiated thyroid cancer. American Thyroid Association. Arch Intern Med 1996; 156: 2165-72.

  7. Passler C, Prager M, Scheuba C, Kaserer K, Flores JA, Vierhapper H, et al The value of fine-needle aspiration biopsy (FNAB) in the differential diagnosis of the “cold” thyroid nodule. Wien Klin Wochenschr 1999; 111: 240-5.

  8. Hurtado-López LM, Arellano-Montaño S, Martinez-Duncker C, Torres-Acosta EM, Zaldivar-Ramirez FR, Duarte-Torres RM, et al. Biopsia de tiroides por aspiración, con aguja fina, no diagnóstica. ¿Qué hacer? Cir Gen 2003; 25: 14-18.

  9. Yeh MW, Demircan O, Ituarte P, Clark OH. False-negative fineneedle aspiration cytology results delay treatment and adversely affect outcome in patients with thyroid carcinoma. Thyroid 2004; 14: 207-15.

  10. Boyd LA, Earnhardt RC, Dunn JT, Frierson HF, Hanks JB. Preoperative evaluation and predictive value of fine-needle aspiration and frozen section of thyroid nodules. J Am Coll Surg 1998; 187: 494-502.

  11. Giuffrida D, Gharib H. Controversies in the management of cold, hot, and occult thyroid nodules. Am J Med 1995; 99: 642-50.

  12. Demirel K, Kaputo O, Yucel C, Ozdemir H, Ayvaz G, Taneri F. A comparison of radionuclide thyroid angiography, (99m)Tc-MIBI scintigraphy and power Doppler ultrasonography in the differential diagnosis of solitary cold thyroid nodules. Eur J Nucl Med Mor Imaging 2003; 30: 642-50.

  13. McHenry CR, Walfish PG, Rosen IB. Non-diagnostic fine needle aspiration biopsy: a dilemma in management of nodular thyroid disease. Am Surg 1993; 59: 415-9.

  14. Chow LS, Gharib H, Goellner JR, van Heerden JA. Nondiagnostic thyroid fine-needle aspiration cytology: management dilemmas. Thyroid 2001; 11: 1147-51.

  15. Hurtado-López LM, Arellano-Montaño S, Torres-Acosta EM, Zaldivar Ramírez FR, Duarte-Torres RM, Alonso-de Ruiz P, et al. Combined use of fine needle aspiration biopsy, MIBI scans and frozen section biopsy offers the best diagnostic accuracy in the assessment of the hypofunctioning solitary thyroid nodule. Eur J Nucl Med Mol Imaging 2004. En prensa.

  16. Taylor A Jr, Murray D, Herda S, Vansant J, Alazraki N. Dynamic lymphoscintigraphy to identify the sentinel and satellite nodes. Clin Nucl Med 1996; 21: 755-8.

  17. Krag DN, Weaver DL, Alex JC, Fairbanks JT. Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe. Surg Oncol 1993; 2: 335-40.

  18. Giuliano AE, Kirgan DM, Guenther JM, Morton DL. Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Ann Surg 1994; 220: 391-8; discussion 398-401.

  19. Valdes-Olmos RA, Tanis PJ, Hoefnagel CA, Jansen L, Nieweg OE, Meinhardt W, et al. Penile lymphoscintigraphy for sentinel node identification. Eur J Nucl Med 2001; 28:581-5.

  20. Giuliano AE. Mapping a pathway for axillary staging: a personal perspective on the current status of sentinel lymph node dissection for breast cancer. Arch Surg 1999; 134: 195-9.

  21. Morton DL. Intraoperative lymphatic mapping and sentinel lymphadenectomy: community standard care or clinical investigation? Cancer J Sci Am 1997; 3: 328-30.

  22. Uren RF, Thompson JF, Howman-Giles B. Lymphatic drainage of the skin and breast. Locating the sentinel nodes. Harwood Academic Publishers. 1999 ISBN 90-5702-410-1.

  23. Gershenwald JE, Thompson W, Mansfield PF, Lee JE, Colome MI, Tseng CH, et al. Multi institutional melanoma lymphatic mapping experience: the prognostic value of sentinel lymph node status in 612 stage I or II melanoma patients. J Clin Oncol 1999; 17: 976-83.

  24. Joseph E, Brobeil A, Cruse CW, Wells K, Costello D, Reintgen DS. Lymphatic mapping for melanomas of the upper extremity. J Hand Surg (Am) 1999; 24: 675-81.

  25. Reintgen D, Albertini J, Milliotes G, Marshburn J, Cruse CW, Rappaport D, et al. Investment in new technology research can save future health care dollars. J Fla Med Association 1997; 84: 175-81.

  26. Mishkin FS. Radionuclide salivary gland imaging. Semin Nucl Med 1981; 11: 258-65.

  27. Goretzki PE, Dotenzrath C, Roeher HD. Management of primary hyperparathyroidism caused by multiple gland disease. World J Surg 1991; 15: 693-7.

  28. Casas AT, Burke GJ, Sathyanarayana, Mansberger AR Jr, Wei JP. Prospective comparison of technetium-99m-sestamibi/iodine-123 radionuclide scan versus high resolution ultrasonography for the preoperative localization of abnormal parathyroid glands in patients with previously unoperated primary hyperparathyroidism. Am J Surg 1993; 166: 369-73.

  29. Gimlette TM, Taylor WH. Localization of enlarged parathyroid glands by thallium 201 and technetium 99m subtraction imaging: Gland mass and parathormone levels in primary hyperparathyroidism. Clin Nucl Med 1985; 10: 235-9.

  30. Lange JR, Nortan JA. Surgery for persistent or recurrent primary hyperparathyroidism. Curr Pract Surg 1992; 4: 56-62.

  31. Akerström G, Rudberg C, Grimelius L, Johansson H, Lundstrom B, Rastad J. Causes of failed primary exploration and technical aspects of reoperation in primary hyperparathyroidism. World J Surg 1992; 16: 562-8; discussion 568-9.

>Journals >Cirujano General >Year 2004, Issue 3

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