2010, Number 2
<< Back Next >>
Cir Gen 2010; 32 (2)
Comparative prospective study; laparoscopic gastric bypass vs. laparoscopic vertical gastrectomy. Effects on the metabolic syndrome. One-year results
Gálvez-Valdovinos R, Marín SE, Funes-Rodríguez F, Mendoza-Rodríguez A, Arellano G, Flores-Martínez J, López-Ambriz G, Hernández-López R
Language: Spanish
References: 19
Page: 83-89
PDF size: 137.11 Kb.
ABSTRACT
Objective: To compare prospectively the effects of gastric bypass
vs sleeve gastrectomy on the metabolic syndrome.
Setting: Hospital Angeles Leon. Third level health care, City of Leon, Gto. Mexico.
Design: Not controlled clinical assay.
Statistical analysis: Student’s t-test.
Patients and methods: From 2005 to 2010 we studied 20 patients with morbid obesity and metabolic syndrome. For this study, two groups were formed: GI, with 10 patients subjected to laparoscopic Roux en Y gastric bypass. GII, including 10 patients subjected to laparoscopic vertical gastrectomy. We assessed statistically anthropometric values, arterial hypertension, central obesity, glucose in blood, triglycerides, and HDL-cholesterol.
Results: The body mass index remained within the curve similarly in both groups, without statistical difference. Arterial hypertension became normal in both groups from the first week on, and has remained normal during the follow-up time, one year after surgery. Glucose and triglyceride values normalized symmetrically in both groups, without statistical differences. HDL-cholesterol increased satisfactorily in both groups without statistically significant differences. Central obesity decreased to less than 100 cm in 3 months, and continued ascending during the follow-up year in both groups, without statistically significant differences. In this study, the metabolic syndrome was corrected in 100% of the patients, without difference in the used surgical technique before the weight loss became significant.
Conclusion: The laparoscopic Roux en Y gastric
bypass and the laparoscopic vertical gastrectomy are effective surgical procedures to treat obesity and the metabolic syndrome at one year of follow-up. There were no differences when comparing both techniques in regard to solving co-morbidities.
REFERENCES
Rosales-Calderón M. Impacto de la cirugía bariátrica sobre el síndrome metabólico. Rev Mex Cir Endoscop 2008; 9: 177-182.
Sjostrom L, Narbro K, Sjostrom CD, Karason K, Larson B, Wedel H, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 2007; 357: 741-52.
Ali MR, Fuller WD, Rasmussen J. Detailed description of early response of metabolic syndrome after laparoscopic Roux-en-Y gastric bypass. Surg Obes Relat Dis 2009; 5: 346-51.
Iannelli A, Anty R, Piche T, Dahman M, Gual P, Tran A, et al. Impact of laparoscopic Roux-en-Y gastric bypass on metabolic syndrome, inflammation, and insulin resistance in super versus morbidly obese women. Obes Surg 2009; 19: 577-82.
Hossain P, Kawar B, El Nahas M. Obesity and diabetes in the developing world - a growing challenge. N Engl J Med 2007; 356: 213-5.
Carvalho PS, Moreira CL, Barelli Mda C, Oliveira FH, Guzzo MF, Miguel GP, et al. Seixas P, Lavinge C, da costa M. Can bariatric surgery cure metabolic syndrome? Arq Bras Endocrinol Metabol 2007; 51: 79-85.
Gil A, Pantoja MJP. Cirugía metabólica. Rev Mex Cir Endoscop 2008; 9: 183-187.
Pories WJ, Swanson MS, MacDonals KG, Long SB, Morris PG, Brown MD, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Ann Surg 1995; 222: 339-352.
Zorrilla BPG, Núnez JN, Tristán PAF. Resultados a largo plazo del bypass gástrico laparoscópico. Rev Mex Cir Endoscop 2008; 9: 151-157.
Lee WJ, Huang MT, Wang W, Lin CM, Chen TC, Lai IR. Effects of obesity surgery on the metabolic syndrome. Arch Surg 2004; 139: 1088-92.
Maggard MA, Shugamman LR, Suttorp M, Maglioni M, Sugerman HJ, Livingston EH, et al. Meta-analysis: surgical treatment of obesity. Ann Intern Med 2005; 142: 547-59.
Tuck ML. Obesity, the sympathetic nervous system, and essential hypertension. Hypertension 1992; 19: 67-77.
Tack CJ, Smits P, Willemsen JJ, Lenders JW, Thien T, Lutterman JA. Effects of insulin on vascular tone and sympathetic nervous system in NIDDM. Diabetes 1996; 45: 15-22.
Neter JE, Stam BE, Kok FJ, Grobbee DE, Gleijnse JM. Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials. Hypertension 2003; 42: 878-84.
Reaven GM, Chen YD, Jeppesen J, Maheux P, Krauss RM. Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles. J Clin Invest 1993; 92: 141-146.
Laws A, Reaven GM. Evidence for an independent relationship between insulin resistance and fasting plasma HDL-cholesterol, triglyceride and insulin concentrations. J Intern Med 1992; 231: 25-30.
López CJA, Guzmán CF, Ortega PF, Hermosillo VC, Calleja EC, Torres MJ. Manga gástrica laparoscópica como procedimiento bariátrico único. Rev Mex Cir Endoscop 2008; 9: 165-169.
Batsis JA, Romero-Corral A, Collazo-Clavell ML, Sarr MG, Sommers VK, Lopez-Jimenez F. Effect of bariatric surgery on the metabolic syndrome: a population-based, long-term controlled study. Mayo Clin Proc 2008; 83: 897-906.
Peterli R, Wölnerhanssen B, Peters T, Devaux N, Kern B, Chritoffel-Courtin C, et al. Improvement in glucose metabolism after bariatric surgery: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy. A prospective randomized trial. Ann Surg 2009; 250: 234-241.