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2010, Number 2

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Cir Gen 2010; 32 (2)

Postoperative pain in laparoscopic cholecystectomy. Ropivacaine vs placebo. Clinical assay

Dávila FSA, Chávez CRH
Full text How to cite this article

Language: Spanish
References: 8
Page: 96-99
PDF size: 127.10 Kb.


Key words:

Ropivacaine, post-operative pain, laparoscopic cholecystectomy.

ABSTRACT

Objective: To compare the efficacy of 7.5% ropivacaine against that of 0.9% saline solution for postoperative pain of elective laparoscopic cholecystectomy.
Setting: Christus Muguerza Hospital, Saltillo, Coah, Mexico.
Design: Double blind clinical assay.
Statistical analysis: Results were analyzed with the SPSS 11 software for Mac, using simple frequencies, central tendency measures and Mann-Whitney U test.
Patients and methods: Forty patients programmed for elective laparoscopic cholecystectomy, with clinical diagnosis of cholelithiasis confirmed through echography. Patients received randomly either ropivacaine or sodium chloride (contained in sterile 20 ml syringes, prefilled and coded by SAFE, in identical presentation). Postoperative pain was measured at 6, 12, 18, and 24 h, by means of the analogic visual scale.
Results: No differences existed regarding either gender, age, and postoperative pain at 6, 12, 18 y 24 h or use of rescue analgesics.
Conclusions: We were unable to demonstrate in this study the efficacy of ropivacaine to control postoperative pain as published by other authors; probably because of the use of higher analgesic doses, which, by itself, could suffice to control pain in both groups.


REFERENCES

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  2. Santeularia VMT, Catalŕ PE, Genové CM, Revuelta RM, Moral GMV. Nuevas tendencias en el tratamiento del dolor postoperatorio en cirugía general y digestiva. Cir Esp 2009; 86: 63-71.

  3. Sorkin LS, Wallace MS. Acute pain mechanisms. Surg Clin North Am 1999; 79: 213-29.

  4. Louizos AA, Hadzilla SJ, Leandros E, Kouroukli IK, Georgiou LG, Bramis JP. Postoperative pain relief after laparoscopic cholecystectomy: a placebo-controlled double-blind randomized trial of preincisional infiltration and peritoneal instillation of levobupivacaine 0.25%. Surg Endosc 2005; 19: 1503-1506.

  5. McCaffery M, Beebe A. Pain: Clinical manual for nursing practice. Baltimore, V.V. Mosby Company. 1993.

  6. Pappas-Gogos G, Tsimogiannis KE, Zikos N, Nikas K, Manataki A, Tsimoyannis EG. Preincisional and intraperitoneal ropivacaine plus normal saline infusion for postoperative pain relief after laparoscopic cholecystectomy: a randomized double-blind controlled trial. Surg Endosc 2008; 22: 2036-2045.

  7. Reynolds F. Ropivacaine. Anaesthesia 1991, 46: 339-340.

  8. Pyati S, Gan TJ. Perioperative pain management. CNS Drugs 2007; 21: 185-211.




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Cir Gen. 2010;32