Ramos-Reyna E, Figueroa-Medina MJ, García-Hurtado JP

Language: Spanish
References: 5
Page: 237-241
PDF size: 117.96 Kb.

ABSTRACT

Migraine is a disabling, common and chronic neurovascular disorder, that is characterized by moderate to severe headache attacks, accompanied of varied symptomatology. It has been assumed that one of the causes of the pain is the activation of the trigeminal nerve. Migraine is a well known cause of economic loss due to the decreased productivity and labor day loss. Objective: to demonstrate the effectiveness of intranasal tetracaine in treatment of acute attack of migraine and to evaluate its side effects. Material and methods: there was carried out a clinical, experimental, pilot, longitudinal, descriptive and comparative study, using intranasal tetracaine compared with placebo (isotonic saline solution 0.9 %). Thirty six patients with acute attack of migraine were included, who arrived to the emergency room and outpatient clinic of neurology. Eighteen patients were treated with tetracaine and 18 patients with placebo. Results: relief of pain was observed in 83% of patients treated with intranasal tetracaine in the first 10 minutes after the application, compared with only 6% in patients treated with placebo. This represents a statistically significant difference (p ‹ 0.0001). Only numbness throat was observed as side effect in patients treated with tetracaine.

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