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2009, Number 2

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Patol Rev Latinoam 2009; 47 (2)

Extensive sclerosing adenosis of the prostate

Saravia FM, Eugenia PA, Leonel AV, Orozco R
Full text How to cite this article

Language: Spanish
References: 6
Page: 125-127
PDF size: 148.55 Kb.


Key words:

prostate, sclerosing adenosis.

ABSTRACT

Sclerosing adenosis of the prostate is an infrequent lesion histologically characterized by a glandular proliferation with basal cells showing mioepithelial differentiation admixed in cellular spindle cell stroma. Sclerosing adenosis can be misdiagnosed as adenocarcinoma, especially when nuclear atypia and prominent nucleoli are present. The majority of the cases have single nodules confined to the transition zone. We present the case of an extensive sclerosing adenosis of prostate in a 77 years old male patient, affecting approximately 50% of the prostatic volume.


REFERENCES

  1. Luque RJ, Lopez-Beltran A, Perez-Seoane C, Suzigan S. Sclerosing adenosis of the prostate. Histologic features in needle biopsy specimens. Arch Pathol Lab Med 2003;127(1):e14-6.

  2. Chen KT, Schiff JJ. Adenomatoid prostatic tumor. Urology 1983;21(1):88-9.

  3. Young RH, Clement PB. Sclerosing adenosis of the prostate. Arch Pathol Lab Med 1987;111(4):363-6.

  4. Helpap B. Differential diagnosis of glandular proliferations in the prostate. A conventional and immunohistochemical approach. Virchows Arch 1998;433(5):397-405.

  5. Berney DM, Fisher G, Kattan MW, Oliver RT, et al. Pitfalls in the diagnosis of prostatic cancer: retrospective review of 1791 cases with clinical outcome. Histopathology 2007;51(4):452-7.

  6. Grignon DJ, Ro JY, Srigley JR, Troncoso P, Raymond AK, Ayala AG. Sclerosing adenosis of the prostate gland. A lesion showing myoepithelial differentiation. Am J Surg Pathol 1992;16(4):383-91.




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Patol Rev Latinoam. 2009;47