Velázquez LA, Quant DC, Ruiz PG

Language: Spanish
References: 11
Page: 77-79
PDF size: 111.44 Kb.

ABSTRACT

Mucormycosis is an opportunistic infection caused by fungi belonging to zigomycete-class. This article presents a 40-year-old male whose entity started with acute diarrhea with hypovolemic shock 15 days before he was entered to Instituto Nacional de la Nutrición Salvador Zubirán, where we found him hypotensive, tachycardic, confused and postrated as well as with polypnea, diaphoresis and mild deshydratation. Thorax radiography showed an extensive consolidation area at left parahiliar region. Patient was hospitalized at intensive therapy unit where a broncoscopy and transbronchial biopsy were made. Mucor spp was isolated in cultures. We started treatment with amphotericin B 1 mg/kg/d. Patient satisfactorily evolved, and was discharged having an amphotericin B accumulated dose of 1.5 g. At this moment he does not have clinical sequelae and a control thorax axial tomography revealed a complete resolution of pneumonic process, even though a pulmonary fibrosis image at left lung apical region persists. Mucormycosis is acquired by inhaling the microorganism. A previous bacterial infection may make easier the superinfection by Mucor. The successful treatment of pulmonary mucormycosis is generally achieved with an early diagnosis and antifungal therapy and with the control of the underlying disease, amphotericin B continues to be the most reliable agent to treat mucormycosis.

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