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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2010, Number 02

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Ginecol Obstet Mex 2010; 78 (02)

Comparison of dinoprostone (ovules and gel) to achieve cervical ripening in patients with term pregnancy that occurs with premature membranes rupture

López-Farfán JÁ, Gámez-Guevara C
Full text How to cite this article

Language: Spanish
References: 13
Page: 110-115
PDF size: 473.93 Kb.


Key words:

Dinoprostone (ovules, gel), cervical maturation, term pregnancy, premature rupture of membranes.

ABSTRACT

Background: Premature rupture of membranes is a normal occurrence of labor and can occur before or after the onset of contractions. The clinical factors associated with premature rupture of membranes include: low socioeconomic status, low body mass index, prior preterm pregnancies, smoking, sexually transmitted infections and urinary tract, conization, cervical cerclage and amniocentesis.
Objective: To evaluate whether prolonged release of the vaginal insert of PGE2 is superior to dinoprostone gel to achieve cervical ripening in patients with term pregnancy that occur with premature rupture of membranes.
Material and method: Randomized clinical trial in the surgical unit of play in a period of 6 months, with an estimated sample of 50 patients was randomized by block table. After assessment confirming rupture of membranes, Bishop Score and meeting inclusion criteria, group A was applied PGE2 intracervical gel 0.5 mg with a maximum of 3 doses, every 6 hours. Group B was administered at vaginal insert of PGE2 single dose for 24 hours, the patient was left to sleep 30 minutes cardio toco-monitoring chart for at least 2 hours after application.
Results: The average time to maturity was 310.59 minutes with a standard deviation of 198.7 and concluded that there was no significant difference between the onset of uterine activity and the onset of labor among the prolonged release dinoprostone and alternatives such as the gel cervical for cervical ripening.
Conclusions: Either this is a good choice to ripen the cervix in patients with term pregnancy and premature rupture of membranes.


REFERENCES

  1. Meis PJ, Ernest JM, Moore ML. Causes of low births weight births in public and private patients. Am J Obstet Gynecol 1987;156:1165-1168.

  2. Tucker JM, Goldenberg RL, Davis RO, et al. Etiologies of preterm birth in an indigent population: is prevention a logical expectation? Obstet Gynecol 1991;77:343-347.

  3. Robertson PA, Sniderman SH, Laros Jr RK, et al. Neonatal morbidity according to gestational age and birth weight from five tertiary care centers in the United States, 1983 through 1986. Am J Obstet Gynecol 1992;166:1629-1645.

  4. Martin JA, Hamilton BE, Sutton PD, et al. Births: final data for 2002. Natl Vital Stat Rep 2003;52:1-116.

  5. Skinner SJM, Campos GA, Liggins GC. Collagen content human amniotic membranes: effect of gestation length and premature rupture. Obstet Gynecol 1981;57:487-489.

  6. Taylor J, Garite T. Premature rupture of the membranes before fetal viability. Obstet Gynecol 1984;64:615-620.

  7. Parry S, Strauss JF. Premature rupture of the fetal membranes. N Engl J Med 1998;338:663-668.

  8. Bishop EH. Pelvic scoring for elective induction of labor. Obstet Gynecol 1964;24:266-301.

  9. Norman M. Prostaglandin E2 induced ripening of the human cervix involves changes in proteoglycan metabolism. Obstet Gynecol 1993;82:1013-1020.

  10. Induction of labor (ACOG Technical Bulletin). Int J Gynecol Obstet 1996;53:65.

  11. Ottinger WS, Menard MK, Brost BC. A randomized clinical trial of prostaglandin E2 intracervical gel and a slow release vaginal pessary for preinduction cervical ripening. Am J Obstet Gynecol 1998;179:349-353.

  12. Hughes EG, Kelly AJ, Kavanagh J. Dinoprostone vaginal insert for cervical ripening and labor induction: a meta-analysis. Obstet Gynecol 2001;97:847-855.

  13. Perry MY, Leaphart WL. Randomized trial of intracervical vs posterior fornix dinoprostone for induction of labor. Obstet Gynecol 2004;103:13.




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Ginecol Obstet Mex. 2010;78