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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2010, Number 11

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Ginecol Obstet Mex 2010; 78 (11)

Primer embarazo logrado por ciclo natural modificado en una paciente baja respondedora en el Centro Médico Nacional 20 de Noviembre, ISSSTE

Mejía-Medina CB, Moreno-García JD, Regalado MA
Full text How to cite this article

Language: Spanish
References: 6
Page: 617-620
PDF size: 330.51 Kb.


Key words:

first pregnancy, fertilization in vitro, modified natural cycle, poor response, oocyte donation program.

ABSTRACT

There was a patient who went to fertilization in vitro, the control ovarian stimulation was using GnRHa in the luteal phase and FSHr 500 IU, she had poor response so she went into a new stimulation protocol using GnRH antagonist. The follow up was made since the 3rd day of menstruation with ultrasound scans, when the follicle reached 14 mm, the antagonist was started with minimal dosage of FSHr until the administration of hCG 10,000 IU. Oocyte retrieval was performed 36 hours later. The embryo transfer was made after 72 hours, was transferred 1 embryo quality 1+, 2 cells, 10% fragmentation. This protocol is named natural cycle modified and is an option to achieve a pregnancy in patients with poor response with their own cells, when the patient refused oocyte donation or if there isn’t that kind of program in the reproductive center like us because is not allowed.


REFERENCES

  1. Schoolcraft WB. Evaluation and treatment of the poor responder. Clin Obstet Gynecol 2006;49(1):23-33.

  2. Faddy MJ, Gosden RG, Gougeon A, Richardson SJ, Nelson JF. Accelerated disappearance of ovarian follicles in midlife: implications for forecasting menopause. Hum Reprod 1992;7:1342-1346.

  3. Bassil S, Godin PA, Donnez J. Outcome in-vitro fertilization through natural cycle in poor responders. Hum Reprod 1999;14:1262-1265.

  4. Feldman B, Seidman DS, Levron J, Bider D, et al. In vitro fertilization following natural cycles in poor responders. Gynecol Endocrinol 2001;15:328-334.

  5. Lindheim SR, Vidali A, Ditkoff E, Sauer MV, Zinger M. Poor responders to ovarian hyperstimulation may benefit from an attempt at natural cycle oocyte retrieval. J Assist Reprod Genet 1997;14:174-176.

  6. Kably AA, Estévez González S. Reproducción asistida: a 30 años del primer nacimiento de fertilización in vitro. Rev Mex Reprod 2009;1(3):89-95.




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C?MO CITAR (Vancouver)

Ginecol Obstet Mex. 2010;78