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2010, Number 4

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Enf Infec Microbiol 2010; 30 (4)

Postnatal varicella infection in a new born baby. A case report

Lemus VML, Díaz PJE, Espinoza OMM
Full text How to cite this article

Language: Spanish
References: 9
Page: 139-141
PDF size: 127.43 Kb.


Key words:

Postnatal varicella, newborn infant, varicella-zoster virus.

ABSTRACT

BACKGROUND. Postnatal varicella generally occurs after the 12th day of life and spreads by respiratory transmission or direct contact; with a mortality above 37%.
OBJETIVE. To describe a case of postnatal varicella.
CASE DESCRIPTION. A male newborn infant was admitted at age 13 days to the Neonatal Intensive Care Unit, with transposition of the great arteries; one day later he underwent surgical correction Jatene-type. On the 11th post-operative day, he presented fever and the following day a maculo-papular exanthem with vesicular hemorrhagic rash. Hemorrhagic varicella was suspected and treatment with acyclovir was begun. The diagnosis was confirmed by PCR (polymerase chain reaction) for varicella-zoster virus (VZV). He developed purpura, jaundice, with digestive tract and respiratory system hemorrhages, pneumonia and died seven days later.
CONCLUSIONS. Postnatal varicella is unusual, the diagnostic test is PCR for VZV; serology test (IgM VVZ) in newborn infants is useless.


REFERENCES

  1. Kohli U, Rana N. “Congenital Varicella Syndrome: presenting with eye complications”. Indian Pediatr 2006; 43: 653-654.

  2. Smith CK, Arin AM. “Varicella in the fetus and newborn”. Semin Fetal Neonatal Med 2009; 14: 209-217.

  3. Sauerbrei A, Wutzler P. “Neonatal Varicella”. J Perinatol 2001; 21: 545-549.

  4. Solas-Pineda V. “Varicela en pacientes de alto riesgo”. An Pediatr (Barc) 2003; 59: 27-31.

  5. Miller E. Virus de varicela-zoster en Greenough Anne. Infecciones congénitas, perinatales y neonatales. Nueva York, Masson 1995: 221-231.

  6. American Academy of Pediatrics. “Antivíricos contra infecciones no producidas por VIH”. En: Pickering LK (ed). Red Book. Informe del comité de enfermedades infecciosas para 2003. 26ª ed. México. Intersistemas 2004: 766-769.

  7. Martín-Ibañez I, Díaz-González EP, Rodríguez-Miguélez JM, Figueras-Aloy J. “Varicela neonatal: a propósito de un caso con bronconeumonía y edema hermorrágico pulmonar”. An Esp Pediatr 2001; 55: 58-60.

  8. Reina J, Ferrés F, del Valle JM. “Eficacia de las técnicas diagnósticas rápidas en 2 neonatos con varicela postnatal”. An Pediatr (Barc) 2006; 65: 83-90.

  9. Pérez-Escobedo J. Varicela en Infectología Clínica Pediátrica. González Saldaña N. 7a edición. Editorial Mc Graw Hill. México. 2004; 377-399.




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C?MO CITAR (Vancouver)

Enf Infec Microbiol. 2010;30