Moreno RAS

Language: Spanish
References: 17
Page: 96-101
PDF size: 589.79 Kb.

ABSTRACT

Background: Laryngopharyngeal reflux is the result of retrograde refluxate of gastric content into laryngopharynx. Ten percent of patients in otorhinolaryngologic consultation report laryngopharyngeal reflux, which is related with several laryngeal diseases: dysphonia, globus pharyngeus, subglottic stenosis, asthma; upper aerodigestive tract cancer, specially laryngeal. The diagnostic method considered gold standard is the ambulatory esophageal pH monitoring.
Objective: To validate the Spanish version of Reflux Symptom Index for clinical use.
Material and method: Reflux Symptom Index was translated to Spanish and was applied to 34 patients who met the inclusion criteria. Videolaryngoscopy was performed in order to identify another serious illness. Reliability of Reflux Symptom Index was evaluated by means of Cronbach’s alpha. Correlations among variables were analyzed by means of Pearson product-moment correlation coefficient.
Results: Nineteen patients (55.9%) were male. Mean age was 42.15 years (SD 14.83). Mean Reflux Symptom Index scores obtained were 17.12 (SD 10.13), and ranged from 2 to 41 points. The most commonly reported symptoms were excess throat mucus (mean 2.79, SD 1.51); lump sensation in the throat (mean 2.76, SD 1.93) and hoarseness or problem with the voice (mean 2.44, SD 1.76). Cronbach’s alpha reliability index was 0.867. None of items affected internal consistency of the instrument.
Conclusions: Reflux Symptom Index showed good validity and reliability and could have clinical application for screening, diagnosis and treatment follow-up for this condition.

REFERENCES

1. Ford CN. Evaluation and management of laryngopharyngeal reflux. JAMA 2005;294(12):1534-40.

2. Koufman JA. The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. Laryngoscope 1991;101(4pt. 2 Suppl. 53):1-78.

3. Hopkins C, Yousaf U, Pedersen M. Acid reflux treatment for hoarseness (protocol). Cochrane Database Syst Rev 2005;(3). Accession No. 00075320-10000000-03935.

4. Maronian NC, Azadeh H, Waugh P, Hillel A. Association of laryngopharyngeal reflux disease and subglottic stenosis. Ann Otol Rhinol Laryngol 2001;110:606-12.

5. Koufman J, Sataloff RT, Toohill R. Laryngopharyngeal reflux: consensus conference report. J Voice 1996;10:215-6.

6. Cherry J, Siegel CO, Margulies SI. Pharyngeal localization of symptoms of gastroesophageal reflux. Ann Otol Rhinol Laryngol 1970;84:1048-54.

7. Ormseth EJ, Wong RK. Reflux laryngitis: pathophysiology, diagnosis, and management. Am J Gastroenterol 1999;94(10):2812-7.

8. Tauber S, Gross M, Issing WJ. Association of laryngopharyngeal symptoms with gastroesophageal reflux disease. Laryngoscope 2002;112:879-86.

9. Ylitalo R, Lindestad PA, Ramel S. Symptoms, laryngeal findings, and 24-hour pH monitoring in patients with suspected gastroesophago-pharyngeal reflux. Laryngoscope 2001;111:1735-41.

10. Ford CN. Advances and refinements in phonosurgery. Laryngoscope 1999;109:1891-900.

11. Belafsky PC, Postma GN, Koufman JA. Validity and reliability of the reflux symptom index (RSI). J Voice 2002;16(2):274-7.

12. Tamer AM, Joseph CS, Tarek MS. Reflux symptom index versus Reflux index score. Ann Otol Rhinol Laryngol 2007;116(6):436-40.

13. Belafsky PC. Abnormal endoscopic pharyngeal and laryngeal findings attributable to reflux. Am J Med 2003;115(3A):90S-96S.

14. Murray L, Johnston B, Lane A. Relationship between body mass and gastro-oesophageal reflux symptoms: The Bristol Helicobacter Project. Int J Epidemiol 2003;32:645-50.

15. Hanson DG, Jiang JJ. Diagnosis and management of chronic laryngitis associated with reflux. Am J Med 2000;108(Suppl. 4a):1125-35.

16. Halum SL, Postma GN, Johnston C. Patients with isolated laryngopharyngeal reflux are not obese. Laryngoscope 2005;115:1042-5.

17. Paterson WG. Extraesophageal complications of gastroesophageal reflux disease. Can J Gastroenterol 1997;11(Suppl.):45B-50B.