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2009, Number S1

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Rev Med UV 2009; 9 (S1)

Toxicity evaluation of Randia monantha Benth fruit

Méndez VLM, Hernández MMR
Full text How to cite this article

Language: Spanish
References: 6
Page: 42-45
PDF size: 218.46 Kb.


Key words:

Randia monantha Benth, Artemia salina L, toxic activity, “crucetillo”.

ABSTRACT

INTRODUCTION. A preparation of cane liquor and fruit of the “crucetillo” (Randia monantha Benth) is drunk, it empirically, and apparently effective results, to counteract the eff ects of snake bites and stings from poisonous animals in the central zone of Veracruz state. OBJETIVE. To evaluate the toxicity of the drink consumed by locals as an antidote, as well as alcoholic extracts of the fruit, leaves and stems extracts prepared by us in the laboratory. MATERIALS AND METHODS. We used the fruit, leaves and stems of R. monantha Benth; alcoholic extracts used were obtained from sugar cane and ethanol by maceration and the toxicity evaluation was determined by bioassay of Artemia salina L., it also conducted a preliminary assessment of the chemical content of all extracts, using a thin layer chromatography. RESULTS AND CONCLUSIONS. The alcoholic extracts prepared by us as well as the drink prepared by the villagers showed no toxicity with the bioassay used, so the intake of tonic is safe. The separation and purification of the alcoholic extracts is in the process.


REFERENCES

  1. World Health Organization 2005. WHO Guidelines for quality assurance of Traditional Medicine education in the Western Pacific Region.

  2. Stevens, W. D., C. U. Ulloa., A. Pool., y Montiel O. 2001. Flora de Nicaragua. Rubiaceae. Angiospermas (Pandanaceae-Zygophyllaceae) Tomo III Missouri Botanical Garden, pp 2274-2277.

  3. Díaz- García A. El crucetillo “Randia monantha Benth“, contraveneno para animales ponzoñosos en la zona centro del estado de Veracruz. Trabajo de experiencia recepcional para obtener el grado de Ingeniéro Agrónomo. Febrero de 2007.

  4. Sistema Único de Información para la Vigilancia Epidemiológica. Información preliminar. http://www.dgepi.salud.gob.mx/ boletin/2008/sem37/index.htm

  5. McLaughlin, J.L. 1991. Crown Gall Tumours on Potato Disc and Brine Shrimp Lethality: Two Simple Bioassays for Higher Plant Screening and Fractionation. En Methods in Plant Biochemistry, 6, 1-32.

  6. TableCurve Windows, v1.0, Jandel Scientific, San Rafael CA.




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Rev Med UV. 2009;9