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2010, Number 2

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Rev Mex Cir Pediatr 2010; 17 (2)

Dose antibiotic prophylaxis in children operated for uncomplicated acute appendicitis A preliminary study

Jaramillo SJG
Full text How to cite this article

Language: Spanish
References: 7
Page: 65-69
PDF size: 177.38 Kb.


Key words:

Acute pppendicitis, Child, Infection of operative wound, Antibiotic prevention.

ABSTRACT

Objective: To demonstrate that the antibiotic prevention in a dose pre operative avoids, like when manages the affairs for 2 or more doses after the surgery, the appearance of infection of the operative wound in children had an operation on acute not complicated appendicitis
Material and methods: I study cuasi experimentally realized in the Service of General Surgery in children had an operation on acute not complicated appendicitis. Prevention was in use like antibiotic the antibiotic association clindamicina - amikacina, for being the medicines normados for the clinical guide of the Service. They divided in 2 groups: the group To was shaped by 29 children which only received a dose of the association clindamicina - amikacina before the surgery. The group B was shaped by 29 children, who were selected at random simply of a sample stratified of a population of 73 patients. In them one administered, equally, the association clindamicina - amikacina with a dose pre operative and up to 3 doses post operative in appendix cecales congestive and festered, and for 3 days or more in the infected ones.
Results: The minor incident of infection of operative wound in the group To was 11.1 %, and that of the group B was 16.7 %. One met p = 0.494 a level of significancia of 95 %, on having applied the statistical test of difference of proportions for what there did not exist statistically significant difference between both groups with regard to the appearance of infection of the operative wound.
Conclusions:> The antibiotic prevention, in an alone dose pre operative, is useful in the children had an operation on acute not complicated appendicitis avoiding the appearance of infection of operative wound, which takes cost to a minor, with regard to the antibiotics, and it diminishes the hospitable stay.


REFERENCES

  1. Jaramillo A. Apendicitis aguda. En Tratado de Cirugía Pediátrica. A. Jaramillo Ed. 1º ed. CONCYTEC - Lima - Perú. 2006: 379-390

  2. Ashcraft K, Holder T, Cirugía pediátrica, Apendicitis, México: Mc- Graw-Hill, Segunda edición, 1995, 39: 484-491.

  3. Hardin M, Acute appendicitis: review and update. Am Fam Physician 1999; 60: 2027-34.

  4. Hatch E, Clínicas Pediátricas de Norteamérica, Cuadro abdominal agudo en niños,USA: Emalsa S.A, 1985, 32: 1201-1213.

  5. Davenport M, Acute abdominal pain in children. BMJ 1996. Feb. 24, 332 (7029):493- 501.

  6. Mazziotti MV. Marley E.F, Winthrop A.L, Fitzgerald P.G. et al. Histopathologic analysis of interva! appendectomy specimens. Support for the role of iníerval appendectomy. J Pediatr Surg1997; 32(6): 806-809.

  7. Rucinski J. Fabian T. Panagopoulos G. et al. Gangrenous and perforated appendicitis: a meta analytic study of 2532 patients indicates that the incision should be closed primarily. Surgery 2000; 127: 136-141.




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Rev Mex Cir Pediatr. 2010;17