Gállego-Sales Salvador G, Jamaica-Verduzco E, Guerrero-Medrano J

Language: Spanish
References: 8
Page: 283-287
PDF size: 1970.76 Kb.

ABSTRACT

Objective: To provide information on the clinical and histopathological characteristics of renal tumors in patients under forty years of age and to compare them with other age groups.
Methods: Case records were reviewed of patients from two institutions operated on for renal tumors over a periodof seven years whose records were complete. A total of 34 patients were found and 5 of them were under forty years of age. Their clinical and histopathological characteristics were compared.
Results: In the Group 1 patients (those under forty years of age), 4 presented with conventional renal cell carcinoma and 1 presented with leiomyosarcoma. There were 29 patients in Group 2, and 23 presented with clear cell carcinoma, 1 with papillary carcinoma, 1 with chromophobe carcinoma, 2 with transitional cell carcinoma of the renal pelvis, 1 with leiomyosarcoma, and 1 with oncocytoma with microscopic focus of renal cell carcinoma. With the exception of the leiomyosarcoma patient, Group 1 patients have survived from 51-72 months with no tumor activity in spite of tumor anatomopathological characteristics.
Conclusions: Despite the small number of patients in the present study, the authors find patient survival rate striking given that other studies refer to the usually aggressive biological behavior of this pathology.

REFERENCES

1. Campbell S, Novick A, Bukowski R. Renal Tumors. En Wein A, Kavoussi L, Novick A, Partin A, Peters C. Campbell-Walsh Urology, 9a. Ed. Vol. 2 Ed. Saunders; 2007: 1567-1637.

2. Lieber M, Tomera F, Taylor W, Farrow G. Renal adenocarcinoma in young adults: survival and variables affecting prognosis. J Urol 1981;125:164-8.

3. Gómez L, Budía A, Delgado F, et al. Incidental renal cancer in young adults: clinical and histopathological findings. Actas Urol Esp 2007;31:244-9.

4. Sanchez R, Rosser C, Madsen L, et al. Young age is an independent prognostic factor for survival of sporadic renal cell carcinoma. J Urol 2004;171(6 Pt 1):2160-5.

5. Schiff M Jr, Herter G, Lytton B. Renal adenocarcinoma in young adults. Urology 1985;25:357-9.

6. Kantor A, Meigs J, Heston J, Flannery J. Epidemiology of renal cell carcinoma in Connecticut, 1935-1973. J Natl Cancer Inst 1976;57:495-500.

7. Fergany A, Hafez K, Novick A. Long term results of nephron sparing surgery for localized renal carcinoma: 10 year followup. J Urol 2000;163:442-5.

8. Berger A, Crouzet S, Canes D, Haber G, Gill I. Minimally invasive nephron-sparing surgery. Curr Opin Urol 2008;18:462-6.