Gaytán-Escobar E, Muñoz-Islas EI, Colorado-García A, Aguado-López HG, Ibáñez-Marín J, Carrillo-Treviño S, Torres-Medina E

Language: Spanish
References: 9
Page: 301-304
PDF size: 906.61 Kb.

ABSTRACT

The term “burned-out” in reference to the testes refers to complete and spontaneous regression of a testicular tumor to fibrous tissue that is in a metastatic state. Described for the first time in 1927, there are several small series and isolated cases reported in the literature. A clinical case of burnedout testicular tumor is presented here. Patient is a 19-yearold male who presented with chest pain. Cardiopulmonary and genital examinations were unremarkable. Alphafetoprotein, human chorionic gonadotropin, and lactate dehydrogenase levels were elevated. Testicular ultrasound revealed intraparenchymatous calcifications in the left testis, chest X-ray and computed tomography showed pulmonary metastatic lesions, and abdominopelvic computed tomography revealed retroperitoneal tumor activity. Retroperitoneal lesion was biopsied, patient received four bleomycin, etoposide, and platinum chemotherapy cycles, and left radical orchiectomy was performed.
Histopathological biopsy study reported mixed nonseminomatous germ cell tumor (choriocarcinoma 33.3%, endodermal sinus tumor 33.3%, and embryonic carcinoma 33.3%). Histopathological study of left radical orchiectomy specimen reported no tumor activity. At last follow-up tumor markers were negative, there was no progression of metastatic lesions and performance status on the ECOG scale was 0.
This entity usually presents with symptoms secondary to metastatic dissemination. Burned-out tumor should be suspected in men presenting with retroperitoneal adenopathy and normal physical testicular examination. Chemotherapy prior to radical orchiectomy is the most effective treatment for this pathology.

REFERENCES

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