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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2011, Number 06

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Ginecol Obstet Mex 2011; 79 (06)

Influenza H1N1 in obstetric population of a General Hospital in Oaxaca

Calvo AO, Canalizo MYR, Hernández CMJ
Full text How to cite this article

Language: Spanish
References: 9
Page: 344-350
PDF size: 295.5 Kb.


Key words:

Influenza, H1N1 Influenza, pregnant women.

ABSTRACT

Background: In April 2009 are reported the first cases of H1N1 influenza in Mexico, presenting the first death from this cause in the city of Oaxaca in the same month. Different epidemiological reports of pandemics brought to the pregnant and high risk population for complications secondary to infection with influenza H1N1 due to immune status.
Objective: describe the obstetric population infected with H1N1 influenza in the Hospital General Dr. Aurelio Valdivieso of Oaxaca.
Material and method: Retrospective and observational study conducted in pregnant women with suspected infection by the virus of the influenza A/H1N1 served in the General Hospital Aurelio Valdivieso of Oaxaca, Oax in 13 patients with influenza H1N1 confirmed by RTPCR during the pandemic occurred from May 2009 to April 2010.
Results: We reported 27 suspected cases of H1N1 influenza in pregnant women of which 13 were positive by RT-PCR, the cumulative incidence was 1.6 per 1000 pregnant women during the period. The fatality rate was 7.6 per hundred pregnant women affected, one case of maternal death indirectly by fluid and electrolyte imbalance occurred and the attack rate was 0.16 per 100 pregnant women, the main complication of atypical pneumonia occurred in four cases followed by three cases of preeclampsia, infants showed no defects and perinatal outcomes were good to present two cases of admission to the NICU for iatrogenic prematurity without deaths.
Conclusions: H1N1 influenza infection has a high fatality rate in late pregnancy. Perinatal outcomes did not worsen the condition or management.


REFERENCES

  1. Echeverria-Zuno S, Mejía-Arangueré JM. Infection and death from influenza A H1N1 virus in Mexico: a retrospective analysis. The Lancet 2009;10:1-8.

  2. Dawood FS, Jain S, Finelli L, et al. Emergence of novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 2009;361.

  3. Noguera-Sánchez MF, y col. Comunicación del primer caso fatal en el mundo, causado por una nueva cepa humana del virus influenza A (H1N1), en una mujer de Oaxaca, México. Rev Asoc Mex Med Crit y Ter Int 2010;24(3):138-144.

  4. CDC. Outbreak of swine-origin influenza A (H1N1) virus infection-Mexico March-April 2009. MMWR 2009;58:467-470.

  5. CDC Novel influenza A (H1N1) virus infections in three pregnant women United States. April-May 2009. MMWR 2009;58:497-500.

  6. McGeer A, Green KA, Plevneshi A, et al. Toronto Invade Bacterial Diseases Network. Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada. Clin Infect Dis 2007;45:156-175.

  7. Fishburne Jl. Physiology and disease of the respiratory system in pregnancy. J Reprod Med 1979;22:177-189.

  8. CDC. Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2008. MMWR 2008;57.




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Ginecol Obstet Mex. 2011;79