2011, Number 1
Undifferentiated embryonal sarcoma of the liver. Clinicopathologic and immunohistochemical study of 8 cases with emphasis on the differential diagnosis with abdominal tumor in children and young adults
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ABSTRACTUndifferentiated (embryonal) sarcoma of the liver (UESL) is an uncommon, rapidly growing malignant spindle cell tumor that usually occurs in children and young adults. It may show overlap morphology with several other hepatic tumors such as hepatocellular carcinoma, mesenchymal hamartoma, embryonal rhabdomyosarcoma, and varios other sarcomas. To complicate the matters further, the immunohistochemical profile for UESL is neither specific nor diagnostic, showing evidence of widely divergent differentiation. We report herein the clinicopathologic and immunohistochemical finding of eight cases of UESL and the differential diagnosis of abdominal mass in children and young adults.
Pérez-Gómez RM, Soria-Céspedes D, de León-Bojorge B, Ortiz-Hidalgo C. Diffuse membranous immunoreactivity of CD56 and paranuclear dot-like staining pattern of cytokeratins AE1/3, CAM5.2, and OSCAR in undifferentiated (embryonal) sarcoma of the liver. Appl Immunohistochem Mol Morphol 2010;18(2):195-198.