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Archivos de Investigación Materno Infantil

ISSN 2007-3194 (Print)
Órgano de difusión oficial del Instituto Materno Infantil del Estado de México
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2011, Number 1

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Arch Inv Mat Inf 2011; 3 (1)

Síndrome de Guillain-Barré variedad Miller-Fisher. Reporte de un caso

Ostia GPJ, Fuentes CMC
Full text How to cite this article

Language: Spanish
References: 7
Page: 30-35
PDF size: 276.69 Kb.


Key words:

Anti-GQ1b antibody, internal ophthalmoplegia, external ophthalmoplegia, ataxia, areflexia, Miller-Fisher syndrome.

ABSTRACT

Case report: Miller-Fisher Syndrome (MFS) is the most frequent atipic variant of the Guillain-Barré Syndrome. It is characterized by the classic triad of ophthalmoplegia, ataxia and areflexia. We present a case of a patient who developed these clinical findings who we use the IgG GQ1b. Motor or sensory component has less relevance, and declares 5% of cases. Sometimes it can present with bulbar or facial paralysis and be preceded by infection with Campylobacter jejuni. The course of this syndrome is good with complete recovery. In the Miller-Fisher syndrome subclass of immunoglobulin G anti-GQ1b and is also related to previous infections, the antibodies of immunoglobulin G1 are the result of an enteral infection. Discussion: Miller Fisher syndrome is an unusual condition seen in ophthalmologic clinical practice. Although respiratory and digestive infections have been reported as antecedent infectious agents in MFS. The use of the immunoglobulin G part GQ1b is important but the cost of this study difficults the access of it.


REFERENCES

  1. Yuki N, Odaka M, Hirata K. Acute ophthalmoparesis (without ataxia) associated with anti-GQ1b IgG antibody: clinical features. Ophthalmology, 2001; 108: 196-200.

  2. Sánchez-Arjona MB, Franco-Macías E, Villalobos-Chaves F. Síndrome de Miller-Fisher que complica una neumonía aguda por Mycoplasma pneumoniae. Rev Neurol, 2003; 36: 235-237.

  3. Kaida K, Kanzaki M, Morita D, Kamakura K, Motoyoshi K, Hirakawa M et al. Anti-ganglioside complex antibodies in Miller-Fisher syndrome. J Neurol Neurosurg Psychiatry, 2006; 77: 1043-1046.

  4. Sugita A, Yanagisawa T, Kamo T, Takahashi Y, Yuki N. Internal ophthalmoplegia with anti-GQ1b IgG antibody. J Neurol, 2002; 249: 1475-1476.

  5. Chan YC, Wilder-Smith E, Chee MW. Acute ophthalmoplegia with pupillary areflexia associated with anti-GQ1b antibody. J Clin Neurosci, 2004; 11: 658-660.

  6. Martínez VM, et al. Tratamiento del síndrome de Guillain-Barré: ¿inmunoglobulinas o plasmaféresis? Revista de Neurología, España, 1998; 13 (4): 167-169.

  7. Ak M, Berrin K, Turan K, Meral T, Metin T. Cyclosporiasis associated with diarrhoea in an immunocompetent patient in Turkey. Journal of Medical Microbiology, 2004; 53: 251-255.




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Arch Inv Mat Inf. 2011;3