2008, Number 2
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ABSTRACTObjective: The purpose of the study is to evaluate the effect of two years of therapy with human recombinant rHu-EPO in anemia in the patient with Chronic Renal Disease (CRD) in predialysis phase and its effects on the quality of life.
Patients and methods: 20 patients with CRD in predialysis phase were studied. Each one of these patients carried out every visit a complete blood count and blood chemistry; the scale of KDQOL was applied at visit 1 and at the final visit. The initial dose recommended was 50 UI/Kg of rHu-EPO, twice per week, administered by subcutaneous injection during the duration of study, scheduled for 24 months.
Results: The haemoglobin and hematocrit levels increased in all patients included in this project; in general, the quality of life improved in this group of patients compared from baseline.
Discussion: The recombinant human erhytropoietin in patients with chronic renal disease produces positive effects in its general state. We observed sensation of well-being, that is not only explained to correct the anemia, but by the global effect of the medicine.
Conclusions: human recombinant erhytropoietin in a long term produces satisfactory effects in the quality of life; therefore, he is useful in patients with anemia and chronic renal disease.
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