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Perinatología y Reproducción Humana

ISSN 0187-5337 (Print)
Instituto Nacional de Perinatología
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2011, Number 2

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Perinatol Reprod Hum 2011; 25 (2)

Incidence and evolution of acute renal insufficiency in women suffering from severe preeclampsia in an Intensive Care Unit

Orozco-Méndez H, Hernández-Pacheco JA, Estrada-Altamirano A, Hernández-Muñoz VA, Carvajal-Valencia AJ, Coronado-Mestre RE
Full text How to cite this article

Language: Spanish
References: 15
Page: 67-73
PDF size: 131.23 Kb.


Key words:

Acute renal failure, preeclampsia, eclampsia, acute tubular necrosis, oliguria.

ABSTRACT

The preeclampsia-eclampsia presents in 10 percent of the total of pregnancy and represent the first cause of maternal death in Mexico. The renal acute disease is a frequent complication of this group of women. Objective: Determine the incidence of different stages of acute renal failure disease in women who have preeclampsia and eclampsia in an Intensive Care Unit. Material and methods: It makes a cohort study of women who have preeclampsia and eclampsia in an Critical Care Therapies; and the frequency of oliguria, prerenal hiperazotemia and tubular necrosis were determinated from the income to the resolution of pregnancy, at 24 hours and at 72 hours of puerperium. Results: There were studied 314 women with average ages of 27 years (± 7.3 years). And divided in two categories depend of the presence or absence of preeclampsia. The first group (severe preeclampsia) with 264 women and the second group (eclampsy) with 39 women, the frequency of renal injury was 79.7%. There were no difference between the groups in relation with oliguria, 58% vs 46.15% (p = 0.16%), neither in prerenal hiperazoemia 3.4% against 5.1% (p = 0.8), tubular acute necrosis 21.2% vs 30.76% (p = 0.17), the proportion of women with oliguria in the beginning was 72.2% and at the end 12.8% presented tubular acute necrosis, this decrease was significant (p = 0.0001), There were no difference found between groups at 72 hours, in women with tubular acute necrosis (p = 0.1299). Conclusions: The preeclampsia-eclampsia affection is very high; however, the women that developed tubular acute necrosis were 5 to 12%.


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Perinatol Reprod Hum. 2011;25