Pérez-Padilla R, Fernández R, García-Sancho C, Franco-Marina F, Mondragón E, Volkow P

Language: English
References: 9
Page: 334-340
PDF size: 261.16 Kb.

ABSTRACT

Objective. Comparison of routine hospital indicators (consults at the Emergency Room (ER) and hospital admissions) during the 2009 pandemic of the influenza AH1N1 virus at the national referral hospital for respiratory diseases in Mexico City. Material and Methods. The outbreak was from April to mid-May 2009 and two control periods were used: 2009 (before and after the outbreak), and during April-May from 2007 and 2008. Results. During the outbreak total consultation at the ER increased six times compared with the 2007-2008 control period and 11 times compared with the 2009 control period. Pneumonia- or influenza-related ER consultations increased 23.2 and 15.3%, respectively. The rate of nosocomial infection during the outbreak was 13.6 and that of nosocomial pneumonia was 6 per/100 hospital discharges, a two-fold and three-fold increase compared to the control periods respectively. Conclusions. During the outbreak, mean severity of admitted patients increased, with a rise in in-hospital mortality and nosocomial infections rate, including nosocomial pneumonia.

REFERENCES

1. CDC. Update: infections with a swine-origin influenza A (H1N1) virus--United States and other countries, April 28, 2009. MMWR Morb Mortal Wkly Rep 2009; 58:431-433.

2. CDC. Swine Influenza A (H1N1) infection in two children--Southern California, March-April 2009. MMWR Morb Mortal Wkly Rep 2009; 58:400-402.

3. CDC. Update: swine influenza A (H1N1) infections--California and Texas, April 2009. MMWR Morb Mortal Wkly Rep 2009; 58:435-437.

4. Dawood FS, Jain S, Finelli L, et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 2009; 360:2605-2615.

5. WHO. Pandemic Influenza, 2009.

6. Perez-Padilla R, de la Rosa-Zamboni D, Ponce de Leon S, et al. Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico. N Engl J Med 2009; 361:680-689.

7. CDC. CDC protocol of realtime RTPCR for swine influenza A (H1N1). Geneva: World Health Organization, 2009.

8. Jain S, Kamimoto L, Bramley AM, et al. Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009. N Engl J Med 2009; 361:1935-1944.

9. Simonsen L, Clarke MJ, Williamson GD, et al. The impact of influenza epidemics on mortality: introducing a severity index. Am J Public Health 1997; 87:1944-1950.