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2011, Number 4

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Med Cutan Iber Lat Am 2011; 39 (4)

Oral alitretinoin: specific therapy for severe chronic eczema of the hands refractory to corticosteroids

Agusti-Mejias A, Sánchez CJL, Messeguer BF, Alegre MV
Full text How to cite this article

Language: Spanish
References: 14
Page: 197-201
PDF size: 1386.06 Kb.


Key words:

Chronic hand eczcema, refractory hand eczema, oral alitretinoin.

ABSTRACT

Eczema of the hands (EOH) is the most prevalent hand dermatosis and represents an important healthcare, social and personal, and occupational concern for affected individuals. There exist numerous therapies for EOH although with a very limited efficacy. The first line drugs for EOH are moderate to high potency topical corticosteroids. A considerable percentage of these patients do not respond to topical corticosteroid therapy, or just partially. Oral Alitretinoin has been shown to be effective and safe for the treatment of chronic hand eczema refractory to potent topical corticosteroids, and it has been specifically approved for this use. In this article we describe the case of a female patient diagnosed with severe EOH grave, resistant to all previous therapies (topical and systemic) and who was successfully treated with oral Alitretinoin at 30 mg/day, with very good tolerance to the drug.


REFERENCES

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Med Cutan Iber Lat Am. 2011;39