2011, Number 3
Vet Mex 2011; 42 (3)
Pustular vulvovaginitis and balanoposthitis suggestive of caprine herpesvirus-1 infection in goats (Queretaro, Mexico)
Candanosa AIE, Sierra GM, Sánchez CA, Salas GG, Méndez BA, Cobos ML, Álvarez RL
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Infectious pustular vulvovaginitis and balanoposthitis in goats is caused by caprine herpesvirus 1 (CpHV-1), from the Herpesviridae
family Alphaherpesvirinae subfamily, sometimes produces abortion, neonatal enteritis and respiratory disease in
adult goats. In a herd of 244 dairy and meat goats, physical examinations were performed in does and bucks, presenting
vulvar and preputial lesions. Necropsies were done in four discarded animals (one male and two females) and one stillborn;
immunohistochemistry (IHC) with bovine herpesvirus 1 (BHV-1) antibodies in prepuce and vulva samples was carried out.
Penis and prepuce exfoliative cytology was carried out in six bucks. Prepuce biopsies were collected for electron microscopy
and viral isolation. Macroscopically, moderate to severe coalescent multifocal pustular and ulcerative vulvovaginitis was observed;
and severe coalescent multifocal pustular and ulcerative balanoposthitis. Microscopically, different degrees of inflammatory
lesions with presence of eosinophilic and amphophilic intranuclear inclusion bodies were present. In electron microscopy,
the prepuce samples and MBDK cell culture showed several intranuclear viral particles of 150 to 230 nm size. There
was slight epithelial cell positivity in IHC with BHV-1 antibodies in vulva and prepuce histological cuts made at necropsy. In
the viral isolate was observed a cytopathic effect and the presence of viral particles by microscopy electronic suggesting
herpes virus. This is the first documented report suggesting the presence of herpes virus outbreak in caprine herds in Mexico.
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