This journal only 2011, Number 4 Rev Mex Cardiol 2011; 22 (4) Development and Implementation of the support table for the arm during endothelial function studies with ultrasound Gutiérrez-Sánchez B, Cervantes Ó, Martínez GJE, Zamora-Cruz JE, Zárate AJ, Sánchez-Falcón M, Medellín-Ramos B Full text How to cite this article Language: Spanish References: 17 Page: 175-181 PDF size: 252.48 Kb. Key words: Support table, forearm, endothelial function, brachial artery. ABSTRACT Endothelial disfunction, its a condition that starts before seeing atheroma plaques in the coronary arteries. The need to obtain a non-invasive evaluation of the endothelial function measuring the flow mediated dilation (DMF) of the brachial artery, requires of a support for the forearm and fixating over the artery in the same axis than the brachial artery an ultrasound transducer. To realize DMF studies with reduced artifacts we developed and implemented support tables for the forearm and a fixation device for the ultrasound transducer, to obtain adequate measuring precision of DMF. 99 studies were done and analysed from May 2008 to July 2010. With the development of the third table we observe that the artifacts were eliminated almost completely with less than 5% in the variability. The development of ostensive improvements on the support tables and fixation of the transducer that ensures adequate relation between the axis of the transducer with the longitudinal axis of the brachial artery were necessary to obtain adequate DMF studies. REFERENCES Third report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and treatment of high blood cholesterol in adults. Adult treatment panel III. Final Report Circulation 2002; 106: 3143. Czernin J, Barnard RJ, Sun KT, Krivokapich J, Nietzsche E, Dorsey D et al. Effect of short-term cardiovascular conditioning and low-fat diet on myocardial blood flow and flow reserve. Circulation 1995; 92: 197-204. Pitkanen OP, Raitakari OT, Niinikoski H, Nuutila P, Iida H, Voipio-Pulkki LM et al. Coronary flow reserve is impaired in young men with familial hypercholesterolemia. J Am Coll Cardiol 1996; 28: 1705-1711. Yokoyama I, Ohtake T, Momomura S, Nishikawa J, Sasaki Y, Omata M. Reduced coronary flow reserve in hypercholesterolemic patients without overt coronary stenosis. Circulation 1996; 94: 3232-3238. Dayanikli F, Grambow D, Muzik O, Mosca L, Rubenfire M, Schwaiger M. Early detection of abnormal coronary flow reserve in asymptomatic men at high risk for coronary artery disease using positron emission tomography. Circulation 1994; 90: 808-817. Zeiher AM, Drexler H, Wollschlager H, Just H. Endothelial dysfunction of the coronary microvasculature is associated with impaired coronary blood flow regulation in patients with early atherosclerosis. Circulation 1991; 84: 1484-1492. Seiler C, Hess OM, Buechi M, Suter TM, Krayenbuehl HP. Influence of serum cholesterol and other coronary risk factors on vasomotion of angiographically normal coronary arteries. Circulation 1993; 88: 2139-2148. Engler MM, Engler MB, Malloy MJ, Chiu EY, Schloetter MC, Paul SM et al. Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial assessment of risk from lipids in youth (EARLY) Trial. Circulation 2003; 108: 1059-1063. García-Unzueta MT, Gutiérrez-Sánchez JB, de Mier I, Amado JA, Berrazueta JR. Autoantibodies against oxidized LDL and serum total antioxidan status in active cyclists and ex-cyclists. Horm Metab Res 2003; 35: 541-545. Hein TW, Kuo L. LDLs impair vasomotor function of the coronary microcirculation: role of superoxide anions. Circ Res 1998; 83: 404-414. Pitkänen OP, Nuutila P, Raitakari OT, Rönnemaa T, Koskinen PJ, Iida H et al. Coronary flow reserve is reduced in young men with IDDM. Diabetes 1998; 47: 248-254. Di Carli MF, Bianco-Batlles D, Landa ME, Kazmers A, Groehn H, Muzik O et al. Effects of autonomic neuropathy on coronary blood flow in patients with diabetes mellitus. Circulation 1999; 100: 813-819. Corretti MC, Anderson TJ, Benjamin EJ, Celermajer D, Charbonneau F, Creager MA et al. International Brachial Artery Reactivity Task Force: Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilatation of the brachial artery. J Am Coll Cardiol 2002; 39: 257-265. Joannides R, Haefeli WE, Linder L, Richard V, Bakkali EH, Thuillez C et al. Nitric oxide is responsible for flow-dependent dilation of human peripheral conduit arteries in vivo. Circulation 1995; 91: 1314-1319. Anderson TJ, Uehata A, Gerhard MD, Meredith IT, Knab S, Delagrange D et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol 1995; 26: 1235-1241. Celermajer DS, Sorensen KE, Gooch VM, Spiegelhalter DJ, Miller OI, Sullivan ID et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992; 340: 1111-1115. Sidhu JS, Newey VR, Nassiri DK, Kaski JC. A rapid and reproducible on line automated technique to determine endothelial function. Heart 2002; 88: 289-292.