2012, Number 1
Immunomodulator effect of ozone therapy in children with deficiency in immunity mediated by phagocytes
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ABSTRACTA pre-experimental study was conducted before then, in order to assess the effect of immunomodulator of ozone therapy in children with immunodeficiency defects of phagocytemediated immunity. The universe was made up by a total of 18 children with deficiencies in phagocytosis, assisted in the Immunology consultation from September 2009 until June 2010 that met the inclusion and exclusion criteria. Ozone was applied in doses by rectal insufflation stepped up a 40μg/mL concentration, for three months. The variables were assessed 1 month after treatment. It was determined if there are significant differences between determinations before and after of ozone therapy, through T of means comparison test for dependent samples, with a significance level α = 0. 05. There were significant increases in the absolute neutrophil count in 100% of cases and the Leukocyte Phagocytic function significantly improved in a 94% after receiving ozone therapy. The clinical state, qualitatively evaluated, was satisfactory in children treated with ozone and no adverse reactions were reported during treatment. It is suggested this therapeutic approach as immunostimulant therapeutic alternative in the phagocytic deficiency.
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