Luna GMM, Portales PR, Echevarría HF, Valdés JL, Satorre RJ

Language: Spanish
References: 13
Page: 590-596
PDF size: 148.66 Kb.

ABSTRACT

The tumors of the gastrointestinal stroma were originally classified as other type of tumors (leiomyoma, leiomyobastoma or leiomyosarcoma) due to it similar histological appearance; however, the advances in the molecular biology and the immunohistochemistry have allowed its differentiation of other digestive neoplasms and to define them as an own clinical and histopathological entity. This is the case of a black female patient aged 79 presenting with abdominal pain during 3 days of evolution started in the right iliac fossa and then it remains in the low belly accompanied by vomiting, fatigue and weakness. She was operated on and is diagnosed with a stump acute appendicitis and of occlusive type en elderly without to rule out an adhesion occlusion. Carrying out the laparotomy it was found that this not-coagulating cavity was blood-free and also a stalked hemorrhagic tumor with movements towards the terminal ileum. Authors carried out its exeresis resecting approximately 5 cm of small intestine with a termino-terminal suture later. A significant cleaning of peritoneal cavity was carried out with the habitual closure achieving a satisfactory evolution with her discharge at 7 days. Patient remains asymptomatic at one a half year postoperative and biopsy yielded a 5 cm-small intestine tumor with a low grade of malignancy.

REFERENCES

1. Catalana O, De Lutio di Castelguidone, Nunziata A, Da Rosa V, Sian A. Gastrointestinal stromal tumours: pictorial review. Radiol Med. 2005;110(5-6):484-91.

2. Mazur MT, Clark HB. Gastric stromal tumors. Reappraisal of histogenesis. Am J Surg Pathol. 1983;7:507-19.

3. Kindblom LG, Remotti HE, Aldenborg F, Meis-Kindblom JM. Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol. 1998;152:1259-69.

4. Alfred I, Neugut, Judith S, Jacobson, Sung Suh, Raja Mukherjee, Nadir Arber. The Epidemiology of Cancer of the Small Bowel. Cancer Epidemiology, Biomarkers & Prevention. March 1998;7(243):243-51.

5. Barcat Juan A. Sobre los tumores del estroma gastrointestinal. MEDICINA (Buenos Aires) 2002;62:291-4.

6. Amin MB, Ma CK, Linden MD, Kubus JJ, Zarbo RJ. Prognostic value of proliferating cell nuclear antigen index in gastric stromal tumors. Correlation with mitotic count and clinical outcome. Am J Clin Pathol. 1993;100:428-32.

7. Ortega L, Medina M, Saiz-Pardo. Tumores del estroma gastrointestinal. Cambio conceptual de los tumores del estroma gastrointestinal (gists) y criterios de malignidad. Oncología (Barc.). 2004;27(4):109-13.

8. Martín González MA, Fuentes Valdés E, Artiles Ivonnet J, Solares ME, Antonio E, Martín González V, Lima M. Tumor del estroma gastrointestinal y cirugía. Rev Cubana Cir [serie en internet]. 2008 [citado 20 de noviembre de 2011];47(3): Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-74932008000300012&lng=es&nrm=iso

9. Boukovinas IP. Advancing treatment of Gastrointestinal Stromal Tumors (GIST) Annals of Gastroenterology. 2007;20(1):75-7.

10. Tae Hyeon K, Suck Chei C, Chang Soo Choi, Yong-ho Nah. Hemoperitoneum secondary to a ruptured gastric stromal tumor. Gastrointestinal Endoscopy. 2006;63(7):1066-7.

11. Cegarra-Navarro MF, De la Calle MA, Girela Baena E, Garcia-Santos JM, Lloret- Estan F, de Andres EP. Ruptured gastrointestinal stromal tumors: Radiologic findings in six cases. Abdom Imaging. 2005;30(5):535-42.

12. Cantos B, Maximiano C, Hurtado A, Méndez M, Cubedo R. Hemoperitoneo en GIST metastásico. Oncología (Barc.). 2007;30(3):122-4.

13. Thomas RM, Sobin LH. Gastrointestinal cancer: incidence and prognosis by histologic type. SEER population-based data: 1978-1987. Cancer. 1995;75:154-70.