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Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado

2012, Number 1

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Rev Esp Med Quir 2012; 17 (1)

Esferolisis as a treatment of low grade cervical squamous intraepithelial lesions

Trejo SÓA, Fernández RG, López VJL, Gómez ILS, López MMC

Language: Spanish
References: 40
Page: 20-23
PDF size: 158.07 Kb.


ABSTRACT

Background: Infection by the human papillomavirus (HPV) infection is the most common sexually transmitted, affecting individuals between 15 and 49 years of age and is prevalent in less developed regions. 1% of sexually active people suffer an injury clinic for HPV at some point in their lives. Factors related to the injury caused by the virus or the persistence of it are those in which there is a deficiency activates cellular immunity, as in the case of women with lupus erythematosus who take corticosteroids or who have a history of transplantation and smoking, among others. Treatment depends on the morphology, number and distribution of lesions.
Objective: To propose as a therapeutic method to treat the esferolisis with high efficiency, low cost and minimal morbidity, squamous intraepithelial lesions of low grade cervical.
Material and methods: The study was performed at the Regional Hospital of Colposcopy Adolfo Lopez Mateos ISSSTE, from 2003 to 2007, and included 363 patients diagnosed with cervical squamous intraepithelial lesions of low grade, confirmed by smear, colposcopy and handled esferolisis biopsy (removal of the transformation zone), radio frequency and followed for one year. The risk factors identified in the patient group with persistence were: disease human immunodeficiency virus (HIV), diabetes mellitus and lupus erythematosus.
Results: We found a total remission of the squamous intraepithelial lesion low grade in 352 patients (96.9%), with one year follow up, and persistence in 11 women (3.1%). There were no postoperative complications during follow-up special.
Conclusions: Monitoring the immunological factor has an important role in the persistence of the lesions, because when analyzing the results showed that in some joint injuries more than one risk factor such as smoking, steroid intake, number of sexual partners, onset of sexual activity before age 18, diabetes mellitus, human immunodeficiency virus and systemic lupus erythematosus.


REFERENCES

  1. Bosch FX, Lorincz A, Munoz N, et al. The causal relation

  2. between human papillomavirus and cervical cancer. J Clin

  3. Pathol 2002;55:244-265.

  4. Bosch FX, de Sanjosé S. Human papillomavirus and cervical

  5. cancer-burden and assessment of causality. J Natl Cancer

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  7. Parkin D. The global health burden of infection-associated

  8. cancers in the year 2002. Int J Cancer 2006;118:3030-

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  10. Thomas J. Management of women with cervical cancer

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  17. Marylou C, Michelle F. See and treat strategy for diagnosis

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  19. Lancet Oncol 2004;20-80.

  20. Munoz N, Bosch FX, de Sanjose S, et al. Epidemiologic

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  22. cervical cancer. N Engl J Med 2003;348:518-527.

  23. Kataja V, Syrjanen S, Yiskoski M, et al. Risk factors associated

  24. with cervical human papillomavirus infections: a casecontrol

  25. study. Am J Epidemiol 1993;138:735-745.

  26. Feldman J, Chirgwin K, Dehovitz J, Minkoff H. The association

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  28. women. Obstet Gynecol 1997;89:346-350.

  29. Prendiville WD. HPV handbook 1. London: Taylor & Francis,

  30. 2004;42-52.

  31. Bosch FX, Lorincz A, Munoz N, et al. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol 2002;55:244-265.

  32. Bosch FX, de Sanjosé S. Human papillomavirus and cervical cancer-burden and assessment of causality. J Natl Cancer Inst Monogr 2003;(31):3-13.

  33. Parkin D. The global health burden of infection-associated cancers in the year 2002. Int J Cancer 2006;118:3030- 3044.

  34. Thomas J. Management of women with cervical cancer precursor lesions. Obstet Gynecol Clin North Am 2002;29(4):109-206.

  35. National Cancer Institute. Future directions in epidemiologic and preventive research on human papilloma viruses and cancer. Bethesda, Maryland, June 2002. NCI Monogr 2003;31:1-130.

  36. Marylou C, Michelle F. See and treat strategy for diagnosis and management of cervical squamous intraephitelial lesions. Lancet Oncol 2004;20-80.

  37. Munoz N, Bosch FX, de Sanjose S, et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med 2003;348:518-527.

  38. Kataja V, Syrjanen S, Yiskoski M, et al. Risk factors associated with cervical human papillomavirus infections: a casecontrol study. Am J Epidemiol 1993;138:735-745.

  39. Feldman J, Chirgwin K, Dehovitz J, Minkoff H. The association of smoking and risk of condyloma acuminatum in women. Obstet Gynecol 1997;89:346-350.

  40. Prendiville WD. HPV handbook 1. London: Taylor & Francis, 2004;42-52.




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