Villacis FSA, García ME, Carvajal GR, Sahagún FJE, Gutiérrez HR

Language: Spanish
References: 47
Page: 56-59
PDF size: 158.54 Kb.

ABSTRACT

Prostatic lymphoma represents 0.09% of malignant prostate tumors. Presentation includes usual signs of prostatism and most reported cases are discovered incidentally by prostate tissue obtained by transurethral resection of the prostate. The sensitivity by transrectal biopsy is 22%. Prostate lymphoma in most cases is indistinguishable from an adenocarcinoma, and sometimes it is possible to find a prostate poorly defined. Anatomopathological study intense lymphohistiocytic infiltrates are observed. We must take into account the possible existence of a systemic lymph node, so it is convenient to perform a myelogram, a bone marrow biopsy, CT chest and abdomen and bone scan. The diagnosis is confirmed by immunohistochemistry with detection of B cells in the immunostaining. Treatment consists of unclogging with improvement in urinary symptoms and cyclophosphamide-based chemotherapy, adriamycin, vincristine and prednisone + rituximab. We present a case of prostatic lymphoma considering their rarity in order to draw attention to this disease since it is important to suspect diagnosis to conduct a proper therapeutic approach. In this case, we found tumor activity after six cycles of chemotherapy; there were not retroperitoneal lymph nodes in the radiological follow-up.

REFERENCES

1. Lewi HJ, Stewart LD, Seywright M, et al. Urinary tract lymphoma.

2. Br J Urol 1986;58:16.

3. Amat-Cecilia M, Romero-Pérez I, Sevilla F. Linfomas del

4. tracto genitourinario. Revisión de conjunto y aportación

5. de dos casos de localización testicular. Arch Esp Urol

6. 1997;47(19):992-997.

7. Kandel LB, McCullough DL, Harrison LL, et al. Primary renal

8. lymphoma. Cancer 1987;60:386.

9. Lewi HJ, Stewart LD, Seywright M, et al. Urinary tract lymphoma.

10. Br J Urol 1986;58:16.

11. Patel DR, Gómez GA, Henderson ES, et al. Primary prostatic

12. involvement in non-Hodgkin lymphoma. Urology 1988;32:96.

13. Wei-Ching L, Po-Hui C. Primary prostate lymphoma presented

14. as urinary retention in a young male patient: A case

15. report. JTUA 2009;20:86-88.

16. Rodríguez-Ledezma JM, Lopez-Tello J, Picaso M. Linfomas

17. del tracto urinario. Arch Esp Urol 1996;49:587.

18. Pereira-Arias JG, Prieto-Ugidos N, Larrinaga-Simon J, et al.

19. Infiltración prostática primaria por linfoma de Burkitt. Arch

20. Esp Urol 1997;50:906.

21. Lomas-García J, Honrado-Franco E, de la Hera-Magallanes

22. A. Linfoma B de células grande primario de próstata. Presentación

23. de un caso y revisión de la literatura. Patología

24. quirúrgica, 1991.

25. Bostwick DG, Cheng L. Urologic surgical pathology. Edinburgh:

26. Mosby Elsevier, 2008.

27. Bostwick DG, Iczkowski KA, Amin MB, Osborne B. Malignant

28. lymphoma involving the prostate: report of 62 cases. Cancer

29. 1998;83(4):732-738.

30. Cole FH, Martin LR. Lymphosarcoma of the prostate. J Urol

31. 1934;31:803.

32. Martín-Plata C. Linfoma primario de próstata: Presentación

33. de un caso clínico-patológico y revisión de la literatura. Actas

34. Urológicas Españolas 2000;24(5):437-441.

35. Lewi HJ, Stewart LD, Seywright M, et al. Urinary tract lymphoma. Br J Urol 1986;58:16.

36. Amat-Cecilia M, Romero-Pérez I, Sevilla F. Linfomas del tracto genitourinario. Revisión de conjunto y aportación de dos casos de localización testicular. Arch Esp Urol 1997;47(19):992-997.

37. Kandel LB, McCullough DL, Harrison LL, et al. Primary renal lymphoma. Cancer 1987;60:386.

38. Lewi HJ, Stewart LD, Seywright M, et al. Urinary tract lymphoma. Br J Urol 1986;58:16.

39. Patel DR, Gómez GA, Henderson ES, et al. Primary prostatic involvement in non-Hodgkin lymphoma. Urology 1988;32:96.

40. Wei-Ching L, Po-Hui C. Primary prostate lymphoma presented as urinary retention in a young male patient: A case report. JTUA 2009;20:86-88.

41. Rodríguez-Ledezma JM, Lopez-Tello J, Picaso M. Linfomas del tracto urinario. Arch Esp Urol 1996;49:587.

42. Pereira-Arias JG, Prieto-Ugidos N, Larrinaga-Simon J, et al. Infiltración prostática primaria por linfoma de Burkitt. Arch Esp Urol 1997;50:906.

43. Lomas-García J, Honrado-Franco E, de la Hera-Magallanes A. Linfoma B de células grande primario de próstata. Presentación de un caso y revisión de la literatura. Patología quirúrgica, 1991.

44. Bostwick DG, Cheng L. Urologic surgical pathology. Edinburgh: Mosby Elsevier, 2008.

45. Bostwick DG, Iczkowski KA, Amin MB, Osborne B. Malignant lymphoma involving the prostate: report of 62 cases. Cancer 1998;83(4):732-738.

46. Cole FH, Martin LR. Lymphosarcoma of the prostate. J Urol 1934;31:803.

47. Martín-Plata C. Linfoma primario de próstata: Presentación de un caso clínico-patológico y revisión de la literatura. Actas Urológicas Españolas 2000;24(5):437-441.