Martínez-Carballo EM, González-Ramos LA

Language: Spanish
References: 12
Page: 2-6
PDF size: 161.82 Kb.

ABSTRACT

Introduction: Cardiovascular malformations in children with Down Syndrome are common. The surgeries are performed with either palliative or corrective purposes and the use of extracorporeal circulation was used according to the procedure. The purpose of this paper is to present the experience on children with Down Syndrome operated by various congenital and acquired cardiovascular diseases.
Material and Methods: The clinical records of 40 cases with Down Syndrome patients and heart surgery were reviewed during the period of 1992 to 2011, the aim was to record several variables of interest, analyze and apply them to formulas for statistical analysis.
Results: In this report of 40 cases, 33 (83%) were diagnosed with congenital heart disease within the first six months of life, 21 (52%) cases presented pulmonary hypertension prior to surgery. 27 (68%) cases had congenital heart disease with an isolated defect, 12 (30%) patients had more than one heart defect, and 1 (2%) patient had congenital heart disease with additional bacterial endocarditis.
The most common congenital heart disease corrected was persistant ductus arteriosus and was 17 (43%) cases, followed by 10 (25%) AV canal complex heart disease patients, ventricular septal defect in 7 (18%) cases. Corrective surgery was performed in 29 (72%) cases and 11 (28%) palliative surgery. In 28 (70%) cases had postoperative complications and overall mortality was 19 cases (48%).
Discussion: Corrective surgery at an early age took place in 10 (25%) cases during the study period and with high mortality compared with other reports. Corrective surgery for congenital heart disease in Down syndrome is an acceptable option to improve survival and provide better quality of life. Early evaluation is important in cardiovascular clinical syndrome in order to establish the accurate diagnosis and timely surgical treatment.

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