Vega UGA

Language: Spanish
References: 12
Page: 309-315
PDF size: 169.37 Kb.

ABSTRACT

Cowden’s Syndrome is a disease caused by mutation in the PTEN gene, with formation of hamartomas at the level of skin, thyroid, breast, gastrointestinal tract, and even lung. Have a predisposition to malignancies such as thyroid and breast cancer, mainly. It Occurs at any age, with an average age of 39 years at the time of diagnosis, with a slight predominance in women. Due his symptomatic diversity, the Internation Cowden Consortium proposed several clinica criteria for diagnosis. The mucocutaneous lesions are the patognomonic feature. Due its potential malignancy, has a poor prognosis, being the management interdisciplinary.

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