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Revista Mexicana de Patología Clínica y Medicina de Laboratorio

ISSN 0185-6014 (Print)
Órgano oficial de difusión de la Federación Mexicana de Patología Clínica, AC y de la Asociación Latinoamericana de Patología Clínica/Medicina de Laboratorio
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2012, Number 4

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Rev Mex Patol Clin Med Lab 2012; 59 (4)

Determination of reference intervals clinical blood count in the Mexican population

Díaz PP, Olay FG, Hernández GR, Cervantes-Villagrana RD, Presno-Bernal JM, Alcántara GLE
Full text How to cite this article

Language: Spanish
References: 10
Page: 243-250
PDF size: 61.12 Kb.


Key words:

Reference intervals, blood count, hematology, Mexico.

ABSTRACT

The blood count is one test used for hematology diagnostic assessment of a patient. Hematological values of healthy patients may vary according to individual characteristics and environment of a population. Therefore, the hematology reference intervals vary according to age, sex, height, etc. The aim of this study was to determine reference intervals of blood count in the Mexican population. Results of 654,047 individuals of both genders were analyzed. We used the nonparametric method of Tukey for the detection of extreme values and reference intervals determined by the method nonparametric recommended by the Clinical and Laboratory Standards Institute (CLSI) guide in C28-A3. The results obtained showed the variability of the intervals calculated with respect to the reference intervals suggested by the manufacturer of the following parameters: leukocytes, erythrocytes, hemoglobin, MCV, platelets, neutrophils and lymphocytes, in percentage and absolute values. The displacement and amplitude changes in the estimated range, was between genders and among age groups established, so it is important that each clinical laboratory reference intervals determined in the study population and in their analytical procedures.


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Rev Mex Patol Clin Med Lab. 2012;59