2012, Number 6
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Rev Fac Med UNAM 2012; 55 (6)
Sphingosine-1-phosphate and its S1P1 receptor: regulators of the inmune response
Bazúa-Valenti S, García-Sáinz JA
Language: Spanish
References: 7
Page: 53-57
PDF size: 352.42 Kb.
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REFERENCES
Fredriksson R y Schioth HB. The Repertoire of G-Protein– Coupled Receptors in Fully Sequenced Genomes. Mol Pharmacol. 2005;67:1414-25.
Hanson MA, Roth CB, Jo E, Griffith MT, Scott FL, Reinhart G, et al. Crystal Structure of a Lipid G Protein–Coupled Receptor. Science 2012;335:851-5.
Alvarez SE, Milstein S y Spiegel S. Autocrine and paracrine roles of sphingosine-1-phosphate. Trends Endocrinol Metab. 2007;18:300-7.
Rivera J, Proia RL y Olivera A. The alliance of sphingosine- 1-phosphate and its receptors in immunity. Nat Rev Immunol. 2008;8:753-763.
Brinkmann V, Billich A, Baumruker T, Heining P, Schmouder R, et al. Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis. Nat Rev Drug Discov. 2010;9:883-97.
Jackson SJ, Giovannoni G y Baker D. Fingolimod modulates microglial activation to augment markers of remyelination. J Neuroinflammation. 2011;8:76.
Choi JW, Gardell SE, Herr DR, Rivera R, Lee CW, Noguchi Ket al. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation. Proc Natl Acad Sci USA. 2011;108:751-6.
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