2012, Number 5
Med Int Mex 2012; 28 (5)
Urinary Tract Infections. In Vitro Resistance Pattern of E. coli ESBL Quinolone, Trimethoprim-Sulfamethoxazole and Nitrofuroantoin
Rendón MMA, Reyes AA, Rosas BJB, Rodríguez WF
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ABSTRACTObjective: To revise the resistance pattern of E. coli and E. coli BLEE (toward quinolones, nitrofurantoine and trimetoprima-sulfametoxazol) in all urocultives taken between August, 2011 and January, 2012 in Angeles del Pedregal Hospital.
Material and Method: It is a transversal cohort descriptive study. The inclusion criteria were positive urocultives taken between August 2011 up to January 2012, separated in 3 groups: Group A. external, Group B internal and Group C intensive care unit, intensive coronary care and pediatric intensive care unit.
Results: There were included 738 positive urocultives. In group A, TMP/SMZ showed a resistance of 56.46% and a quinolones resistance of (Levofloxacin 29.74%, Ciprofloxacin 8.18% and Norfloxacin 13.36%) and nitrofurantoin 8.18%. Group B presented a resistance of 71.69% to TMP/SMZ, to quinolones (levofloxacin 49.05%, Ciprofloxacin 43.49% and Norfloxacin 26.41%) and nitrofurantoin of 5.6%. In group C was founded a 66.6% resistance to TMP/SMZ, to quinolones (Levofloxacin 66.66%, Ciprofloxacin 66.66% and Norfloxacin 33.33%) and Nitrofurantoin 0%.
Conclusion: There is a high resistance toward TMP/SMZ in all hospital levels. The lower index of resistance in non-complicated, ambulatory UTIS is to ciprofloxacin. In-hospital, the lower resistance is to norfloxacin, while in the intensive care unit should be an individualized treatment.