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2012, Number 2

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Cir Gen 2012; 34 (2)

Sensitivity and specificity of the Alvarado Score in the diagnosis of acute appendicitis as compared with CAT scan and ultrasound during the first 24 hours of evolution

Cedillo AEJ, Santana VIA, González CR, Onofre CJ, Gartz-Tondorf GR
Full text How to cite this article

Language: Spanish
References: 10
Page: 107-110
PDF size: 46.69 Kb.


Key words:

Appendicitis, surgical management, Alvarado score, CT scan, conservative treatment, ultrasound.

ABSTRACT

Objective: To compare the sensitivity and specificity of the Alvarado score for the diagnosis of acute appendicitis with that of computed axial tomography (CAT) scan and ultrasound (US).
Setting: Christus Muguerza High Specialty Hospital, Monterrey (México).
Design: Prospective, comparative, observational, cross sectional study. Statistical analysis: sensitivity, specificity, and positive and negative predictive values. Bayesian analysis.
Patients and methods: Ninety-nine patients with clinical diagnosis suggestive of acute appendicitis with less than 24-hour evolution, subjected to appendicectomy. Patients were clinically evaluated with the Alvarado Score, CAT scan was performed in 43 patients, and abdominal US in 46 patients. We established the diagnostic value of the Alvarado Score by itself and compared it with the diagnostic value of CAT scan and US, as well as with the possibility of negative post-test (PNPT). The histopathological study was the diagnostic gold standard.
Results: Ninety-nine patients evaluated with the Alvarado score, yielded a sensitivity of 73%, specificity of 57%, positive predictive value (PV) of 91% negative predictive value of 26%, PNPT of 32%. CAT scan had a sensitivity of 92%, specificity of 0%, positive PV of 96%, negative PV of 0%, PNPT of 99%. The US revealed a sensitivity of 90%, specificity of 50%, positive PV of 92%, negative PV of 43%, PNPT of 17%.
Conclusion: The Alvarado score continues to be a good diagnostic test for acute appendicitis. US is the best adjuvant imaging test, since when it indicates negativity for appendicitis, the possibility that this is present is of 17%.


REFERENCES

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  2. Fitz RH. Perforating inflammation of the vermiform appendix with special reference to its early diagnosis and treatment. Am J Med Sci 1886; 92: 321.

  3. Andersson RE, Hugander A, Ravn H, Offenbarti K, Ghazi SH, Nyström PO, et al. Repeated clinical and laboratory examinations in patients with an equivocal diagnosis of appendicitis. World J Surg 2000; 24: 479-485.

  4. Al Qahtani HH, Muhammad AA. Alvarado score as an admission criterion for suspected appendicitis in adults. Saudi J Gastroenterol 2004; 10: 86-91.

  5. John H, Neff U, Kelemen M. Appendicitis diagnosis today: clinical and ultrasonic deductions. World J Surg 1993; 17: 243-249.

  6. Jo YH, Kim K, Rhee JE, Kim TY, Lee JH, Kang SB, et al. The accuracy of emergency medicine and surgical residents in the diagnosis of acute appendicitis. Am J Emerg Med 2010; 28: 766-770.

  7. Alvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med 1986; 15: 557-564.

  8. Sivit CJ, Newman KD, Boenning DA, Nussbaum-Blask AR, Bulas DI, Bond SJ, et al. Appendicitis: usefulness of US in diagnosis in a pediatric population. Radiology 1992; 185: 549-552.

  9. Gwynn LK. The diagnosis of acute appendicitis: clinical assessment versus computed tomography evaluation. J Emerg Med 2001; 21: 119-123.

  10. Birnbaum BA, Wilson SR. Appendicitis at the millennium. Radiology 2000; 215: 337-348.




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Cir Gen. 2012;34