>Year 2012, Issue 2
Albarrán CJ, Mendoza MJ, Nevárez BHA
Risk factors for cholecystolithiasis in Young patients with a body mass index below 30
Cir Gen 2012; 34 (2)
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Objective: To determine the risk factors for cholecystolithiasis in young female patients with a body mass index (BMI) ‹ 30.
Setting: Specialty Medical Center of Cd. Juárez, Chihuahua.
Design: Cases and controls study.
Statistical analysis: Percentages as summary measure for qualitative variables and odds ratio (OR).
Patients and methods: We collected data from the clinical records of 20 patients subjected to laparoscopic cholecystectomy from January 2006 to April 2011. Nutritional status was estimated from an interview performed via telephone. The assessed variables were: specialized weight loosing diets, daily fiber consumption, nocturnal fasting period longer than 10 hours, and alcohol consumption.
Results: A positive association was found between the specialized weight losing diets and cholecystolithiasis (OR 2.33; IC 95%, 0.63-5.28, p ‹ 0.05); daily consumption of fiber had a protective action (OR 0.333; IC 95%, 0.27-1.96, p ‹ 0.05); a nocturnal fasting period longer than 10 hours was positively associated with cholecystolithiasis (OR 1.33; IC 95%, 0.29-5.91, p ‹ 0.05). Alcohol consumption had a protective effect (OR 0.42; IC del 95%, 0.11-1.56, p ‹ 0.05).
Conclusions: We found that specialized diets to lose weight and a long nocturnal fasting period are important risk factors for cholecystolithiasis in young women. We also found that the daily consumption of fiber and moderate alcohol consumption diminish the risk for this disease.
||Cholecystolithiasis, etiology, gallstones, fasting.
Kleiner O, Ramesh J, Huleihel M, Cohen B, Kantarovich K, Levi C, et al. A comparative study of gallstones from children and adults using FTIR spectroscopy and fluorescence microscopy. BMC Gastroenterology 2002; 2: 3.
Walcher T, Haenle M, Kron M, Hay B, Mason RA, Walcher D, et al. Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population. BMC Gastroenterology 2009; 9: 74.
González-Hita ME, Bastidas-Ramírez BE, Panduro-Cerda A: Factores de riesgo en la génesis de la litiasis vesicular. Inv Salud 2005; 7: 71-78.
División Técnica de Información Estadística en Salud. El IMSS en Cifras. Las intervenciones quirúrgicas. Rev Med Inst Mex Seguro Soc 2005; 43: 511-520.
Mercado MA. Colecistitis la expansión de un concepto y sus implicaciones. Cir Cir 2002; 70: 303-304.
Mertens MC, Roukema JA, Scholtes VP, De Vries J. Risk assessment in cholelithiasis: is cholecystectomy always to be preferred? J Gastrointest Surg 2010; 14: 1271-1279.
Gaby AR. Nutritional approaches to prevention and treatment of gallstones. Altern Med Rev 2009; 14: 258-267.
Sun H, Tang H, Jiang S, Zeng L, Chen EQ, Zhou TY, et al. Gender and metabolic differences of gallstone diseases. World J Gastroenterol 2009; 15: 1886-1891.
Chen CY, Lu CL, Huang YS, Tam TN, Chao Y, Chang FY, et al. Age is one of the risk factors in developing gallstone disease in Taiwan. Age Ageing 1998; 27: 437-441.
Cho JY, Han HS, Yoon YS, Ahn KS. Risk factors for acute cholecystitis and a complicated clinical course in patients with symptomatic cholelithiasis. Arch Surg 2010; 145: 329-333.
Méndez-Sánchez N, Ponciano-Rodríguez G, Bermejo-Martínez L, Villa AR, Chávez-Tapia NC, Zamora-Valdes D, et al. Low serum levels of ghrelin are associated with gallstone disease. World J Gastroenterol 2006; 12: 3096-3100.
Sichieri R, Everhart JE, Roth H. A prospective study of hospitalization with gallstone disease among women: role of dietary factors, fasting period, and dieting. Am J Public Health 1991; 81: 880-884.
Herzog D, Bouchard G. High rate of complicated idiopathic gallstone disease in pediatric patients of a North American tertiary care center. World J Gastroenterol 2008; 14: 1544-1548.
Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Dietary protein and the risk of cholecystectomy in a cohort of US women: the Nurses’ Health Study. Am J Epidemiol 2004; 160: 11-18.
>Year 2012, Issue 2