2012, Number 2
Rev Mex Med Fis Rehab 2012; 24 (2)
Prevalence of Cardiovascular Autonomic Neuropathy in patients with Type 2 Diabetes Mellitus and the standardization in the Mexican population using heart rate variability (HRV)
Gutiérrez FÁJ, Montes CML, Jiménez OJH
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ABSTRACTObjectives: The aim of this article was to standardize the normal parameters of heart rate variability in 100 healthy subjects, and then determine the frequency of Cardiovascular Autonomic Neuropathy in patients with type 2 diabetes mellitus. Material and methods: A cross section analytical study carried out in two stages: first stage: standardize the test for the heart rate variability in 100 healthy subjects between 40 and 85 years of age according to 3 of 5 test of Ewing’s methodology; second stage: using 41 patients with type 2 diabetes mellitus between 40 and 85 years of age; EMG machine was used for assessing the heart rate variability (HRV) with time analysis to perform the following three tests: 1. deep breathing, 2. standing up, 3. Valsalva maneuver. Analytical statistics were used and it was estimated by T Student that with independent samples and the Pearson coefficient, a correlation was established. Results: One hundred healthy subjects were taken in order to obtain accurate values for reference; 41 subjects who were diagnosed with type 2 diabetes mellitus were thus evaluated. In patients with type 2 DM, more than 60% demonstrated cardiovascular autonomic neuropathy; 41.4% showed autonomic dysfunction and 19.4% showed defined neuropathy. Conclusions: The standardization of heart rate variability (HRV) in the Mexican population as to determine the frequency of cardiovascular autonomic neuropathy, is greater than what had been previously established in international publications.