2012, Number 3
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Rev Cent Dermatol Pascua 2012; 21 (3)
Dowling-Degos disease
Domínguez GMA, Ramos GA, Valencia ÁM
Language: Spanish
References: 14
Page: 99-103
PDF size: 95.63 Kb.
ABSTRACT
Dowling-Degos disease has an autosomal dominant variable penetrance. It is caused by a mutation in chromosome 17 that
produces altered cytokeratins 5 and 14. Clinicaly it is characterized by reticulated hiperpigmented spots that prevails in folds
and it is accompanied by perioral scars and injuries of pimple-like aspect. It’s more frequent in women of the fourth decade of
the life. In this article we report the case of a 40 year old female patient with Dowling-Degos disease.
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