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2012, Number 1

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Invest Medicoquir 2012; 4 (1)

Sistemic amyloidois: presentacion of a case

Morejón FH, Izaguirre RR, Figueredo PI, de Armas FMC, González PJL, Brito PCA
Full text How to cite this article

Language: Spanish
References: 10
Page: 54-60
PDF size: 179.77 Kb.


Key words:

amyloidosis, multiple myeloma, fibrilar proteins.

ABSTRACT

Amyloidosis is characterized for the deposit of proteins of fibrilar, insoluble and ultrastructural type characteristics that mainly deposit at the level of extracellular spaces of organs and ti ssues, but is not a frequent disease. It is typically classified as to biochemical nature of fibrilar protein and which, according to its distribution in the body may be either systemic or localized. The most frequent systemic amyloidosis as to clinical pr actice is the one called AL (primary or associated to a multiple myeloma) whose precursors are light inmunoglobuline chains. A revision of the theme was conducted afterwards, based on a case presentation of a 76 year old female patient diagnosed with amylo idosis associated a multiple myeloma .


REFERENCES

  1. Strege RJ, Saeger W, Linke RP. Diagnosis and immunohistochemical classification of systemic amyloidoses. Report of 43 cases in an unselected autopsy series. Virchows Arch.1998;433(1):19 -27.

  2. Rysavá R. AL amyloidosis with renal involvement. Kidney Blood Press Res. 2007;30(6):359 -64.

  3. Bergesio F, Ciciani AM, Manganaro M, Palladini G, Santostefano M, Brugnano R, et al. Renal involvement in systemic amyloidosis. Nephrol Dial Transplant. 2008;23(3):941 -51.

  4. Sanchorawala V. Light-Chain (AL) amyloidosis: diagnosis and treatment. Clin J Am Soc Nephrol. 2006 Nov;1(6):1331 -41.

  5. Crosthwaite A, Skene A, Mount P. Rapidly progressive glomerulonephritis complicating primary AL amyloidosis and multiple myeloma. Nephrol Dial Transplant. 2010;25(8):2786 -9.

  6. The International Myeloma Working Group. Criteria for the classi fication of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol. 2003;121(5):749-57.

  7. Falk RH, Comenzo RL, Skinner M. The Systemic Amyloidoses. N Engl J Med. 1997;337(13):898 -909.

  8. Sarriegui S, Casanova JM, Baradad M . Amiloidosis sistémica primaria con afectación cutánea. Actas Dermo -Sif. 1994;85(1):31-4.

  9. Villegas C, Roo E, Roustan G. Amiloidosis primaria sistémica asociada a mieloma múltiple. Actas Dermo-Sif. 1993; 84(2):115-7.

  10. Olm M, Alsina M, Villalta J, Grau JM. Systemic amyloidosis presenting as cutaneous lesions. Int J Dermatol. 1991;30(5):364 -6.




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Invest Medicoquir. 2012;4