2012, Number 3
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Rev Mex Cir Endoscop 2012; 13 (3)
Quality of oncological resection in rectal cancer. Comparative study between laparoscopic and open surgery
Ramírez MF, Valadez CD, Enríquez GJA, Vega JM, Cruz SCA, Ramírez MR, Decanini TCÓ
Language: Spanish
References: 33
Page: 127-132
PDF size: 106.69 Kb.
ABSTRACT
Introduction: The rectal cancer is the third most common cancer worldwide. Currently there is consensus on the feasibility of laparoscopic treatment for rectal cancer; however, optimal oncologic resection by this technique is still controversial.
Material and methods: Retrospective, transversal and observational study. Patients undergoing resection for rectal cancer from January 1
st 2004 to September 1st 2011. Variables: Sociodemographic characteristics, perioperative and radicality of the procedure. Analysis: Percentage as a measure of qualitative variables. Student t test for unpaired values. χ
2 for variables expressed as proportions. p ‹ 0.05 statistically significant.
Results: 89 patients, laparoscopic surgery = 39; open surgery = 50. Hospital stay 7.92
versus 10.18 days (p = 0.039). Low anterior resection (LAR): 38 (98%)
versus 32 (64%), abdominoperineal resection (APR): 1 (2%)
versus 18 (36%) (p = 0.0001). Diverting ileostomy: 3 (7.69%)
versus 29 (58%) (p = 0.043). Intraoperative bleeding: 259
versus 525 mL (p = 0.001). Free surgical margins: 100
versus 96% (p = 0.006). Lymph nodes removed: 11.5
versus 13.5 (p = 0.139). Anastomotic dehiscence: 3 (7.6%)
versus 2 (4%) (p = 0.126). Reoperation: 3.
versus 4. (p = 1.631).
Conclusions: The results of treatment of rectal cancer by laparoscopic surgery are equivalent in terms of oncological resection to those observed for open surgery with potential benefits as reduced pain, length of stay and postoperative bleeding.
REFERENCES
Parkin DM, Chen VW, Ferlay J, Galceran J, Storm HH, Whelan SL. Global cancer statistics in the year 2000. Lancet Oncol 2001; 9: 533-543.
American Cancer Society. Cancer facts and figures 2010. Atlanta, Ga: American Cancer Society, 2010.
Dirección General de Estadística-Secretaría de Salud (DGE-SSA). Registro Histopatológico de Neoplasias 2000. México: DGE-SSA, 2000: 7-8, 11-13.
Le Voyer TE, Sigurdson ER, Hanlon AL, Mayer RJ, Macdonald JS, Catalano PJ et al. Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol 2003; 21: 2912-2919.
Kang H, O’Connell JB, Leonardi MJ, Maggard MA, MxGory ML, Ko CY. Rare tumors of the colon and rectum: a national review. Int J Colorectal Dis 2007; 22: 183-189.
Wolpin BM, Meyerhardt JA, Mamon HJ, Mayer RJ. Adjuvant treatment of colorectal cancer. CA Cancer J Clin 2007; 57: 168-185.
Siddiqui AA, Fayiga Y, Huerta S. The role of endoscopic ultrasound in the evaluation of rectal cancer. Int Semin Surg Oncol 2006; 3: 36-41.
Zammit M, Jenkins JT, Urie A, O’Dwyer PJ, Mohillo RG. A technically difficult endorectal ultrasound is more likely to be inaccurate. Colorectal Dis 2005; 7: 486-491.
Goldstein MJ, Mitchell EP. Carcinoembryonic antigen in the staging and follow-up of patients with colorectal cancer. Cancer Invest 2005; 23: 338-351.
The COST study group. Clinical outcomes of surgical therapy study group. A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med 2004; 350: 2050-2059.
Schwenk W, Bohm B, Muller JM. Postoperative pain and fatigue after laparoscopic or conventional colorectal resections. A prospective randomized trial. Surg Endosc 1998; 12: 1131-1136.
Schwenk W, Bohm B, Haase O, Junghans T, Muller JM. Laparoscopic versus conventional colorectal resection: a prospective randomized study of postoperative ileus and early postoperative feeding. Langenbecks Arch Surg 1998; 383: 49-55.
Braga M, Frasson M, Vignali A, Zuliani W, Civelli V, Di Carlo V. Laparoscopic versus open colectomy in cancer patients: long-term complications, quality of life, and survival. Dis Colon Rectum 2005; 48: 2217-2223.
Koopmann MC, Heise CP. Laparoscopic and minimally invasive resection of malignant colorectal disease. Surg Clin N Am 2008; 88: 1047-1072.
Antonio M, García VJ. Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastasic colon cancer. Lancet 2002; 359: 2224-2229.
Milsom JW, Bohm B, Decanini C, Fazio VW. Laparoscopic oncologic proctosigmoidectomy with low colorectal anastomosis in a cadaver model. Surg Endosc 1994; 8: 1117-1123.
Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AM et al. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomized controlled trial. Lancet 2004; 365: 1718-1726.
Leung KL, Kwok SP, Lam SC, Lee JF, Yiu RY, Ng SS et al. Laparoscopic resection of rectosigmoid carcinoma: prospective randomized trial. Lancet 2004; 363: 1187-1192.
Zhou ZG, Hu M, Li Y, Lei WZ, Yu YY, Cheng Z et al. Laparoscopic versus open total mesorectal excision with anal sphincter preservation for low rectal cancer. Surg Endosc 2004; 18: 1211-1215.
Lujan J, Valero G, Hernández Q, Sánchez A, Frutos MD, Parrilla P. Randomized clinical trial comparing laparoscopic and open surgery in patients with rectal cancer. Br J Surg 2009; 96: 982-989.
Ng SS, Leung KL, Lee JF, Yiu RY, Li JC, Teoh AY et al. Laparoscopic-assisted versus open abdominoperineal resection for low rectal cancer: a prospective randomized trial. Ann Surg Oncol 2008; 15: 2418-2425.
Weeks JC, Nelson H, Gelberg S. Short-term quality of life outcomes following laparoscopic assisted colectomy versus open colectomy for colon cancer. JAMA 2002; 16: 321-328.
Colon and rectum. In: American Joint Committee on Cancer. AJCC Cancer Staging Manual. 6th ed. New York, NY: Springer, 2002: 113-124.
Compton CC, Greene FL. The staging of colorectal cancer: 2004 and beyond. Cancer J Clin 2004; 54: 295-308.
Nelson H, Petrelli N, Carlin A, Couture J, Fleshman J, Guillem J et al. Guidelines 2000 for colon and rectal cancer surgery. J Natl Cancer Inst 2001; 93: 583-596.
Swanson RS, Compton CC, Stewart AK, Bland KI. The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined. Ann Surg Oncol 2003; 10: 65-71.
Prandi M, Lionetto R, Bini A, Francioni G, Accarpio G, Anfossi A et al. Prognostic evaluation of stage B colon cancer patients is improved by and adequate lymphadenectomy results of a secondary analysis of a large scale adjuvant trial. Ann Surg 2002; 235: 458-463.
Abel ME, Rosen L, Kodner I, Fleshman JW, Hicks T, Kennedy HL et al. Practice parameters for the treatment of rectal carcinoma -supporting documentation. Dis Colon Rectum 1993; 36: 991-1006.
Wolff BG. Lateral margins of resection in adenocarcinoma of the rectum. World J Surg 1992; 16: 467-469.
Heald RJ, Husband EM, Ryall RD. The mesorectum in rectal cancer surgery. The clue to pelvic recurrence? Br J Surg 1982; 69: 613-616.
Heald RJ, Moran BJ, Ryall RD, Sexton R, MacFarlane JK. Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978-1997. Arch Surg 1998; 133: 894-899.
Jayne DG, Guillou PJ, Thorpe H, Quirke P, Copeland J, Smith AM et al. Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC trial group. J Clin Oncol 2007; 25: 3061-3068.
Sauer R, Becker H, Hohenberger W, Rodel C, Wittekind C, Fietkau R et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004; 351: 1731-1740.