2012, Number 2
Bol Clin Hosp Infant Edo Son 2012; 29 (2)
Diagnostic Approach of Whooping Cough and Coqueluchoid Syndrome.
Cano-Rangel MA, Durazo-Arvizu MÁ, Dorame-Castillo R, Gómez-Rivera N
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Language: Spanish
References: 8
Page: 85-87
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ABSTRACT
Whooping cough is a term used to include those patients with a clinical picture indistinguishable for whopping cough, in addition to not identifying the presence of Bordetella pertussis or parapertussis.The agents involved may include viruses and bacteria, among which H. influenzae, Moraxella catarralis, M. pneumoniae, adenovirus, influenza virus, parainfluenza 1-4, syncitial respiratory virus, cytomegalovirus and Epstein Barr virus stand out.Clinically there are three periods in the evolution of the disease. Catarrhal period: last a few days to 2 weeks, may manifest clinically as an infection of the respiratory tract with runny nose, watery eyes, moderate dry cough occurs. Afterwards increased cough and its severity and the presence of paroxysms start entering in the next period. Paroxysmal period: last 2 to 6 weeks and is characterized by 5 to 10 episodes of coughing forced inspiratory phase, with stridor at the end of paroxysm (phlegm), often accompanied by vomiting, cyanosis and apnea (young infant). In the Convalescence period duration is 2 weeks, symptoms gradually decrease in severity and frequency.
Etiologic diagnosis can be established by culture (Bordet-Gengou or Regan-Lowe modified) by polymerase chain reaction (PCR), by serology in the acute phase and convalescence, by immunofluorescence, and may suspected in CBC findings. We propose a diagnosis algorithm to unify criteria in our institution, avoid underdiagnosis.
REFERENCES
1.- Gómez-Rivera N, García-Zarate M, Álvarez-Hernández G, Villalobos-García L, Fonseca-Chon I, Cano-Rangel M, y cols. Tos Ferina y Síndrome Coqueluchoide en menores de 1 año de edad: factores de riesgo asociados a mortalidad: estudio transversal descriptivo de 48 casos. Bol Clin Hosp Infant Edo Son 2011; 26(1): 2-6.