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2007, Number 6

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Rev Invest Clin 2007; 59 (6)

Analysis of Haptoglobin Phenotype Polymorphism in a Mennonite Population of Northern Mexico

Alvarado-Esquivel C, Delanghe J
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Language: English
References: 5
Page: 491-492
PDF size: 30.84 Kb.


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Haptoglobin (Hp) is a serum protein with a number of biological activities. Hp is expressed by a genetic polymorphism as three major phenotypes: 1-1, 2-1, and 2-2.


REFERENCES

  1. Langlois MR, Delanghe JR. Biological and clinical significance of haptoglobin polymorphism in humans. Clin Chem 1996; 42: 1589-600.

  2. Lisker R, Zárate G, Rodríguez E. Studies on several genetic hematological traits of the Mexican population. XIV. Serum polymorphisms in several Indian tribes. Am J Phys Anthropol 1967; 27: 27-32.

  3. Delanghe J, Langlois M, Alvarado Esquivel C, De Haene H, De Buyzere M. Haptoglobin 1F allele frequency is high among indigenous populations in the state of Durango, Mexico. Hum Hered 2000; 50: 263-5.

  4. Matson GA, Sutton HE, Swanson J, Robinson AR. Distribution of haptoglobin, transferrin, and hemoglobin types among Indians of middle America: southern Mexico, Guatemala, Honduras and Nicaragua. Hum Biol 1963; 35: 474-83.

  5. Smithies O. Zone electrophoresis in starch gels: Group variations in the serum proteins of normal human adults. Biochem J 1955; 61: 629-41.




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Rev Invest Clin. 2007;59