2013, Number 2
Med Crit 2013; 27 (2)
Barriga FP, Pomposo EMA, García DG, Monares ZE, Montes de Oca SMA, Poblano MM, Aguirre SJ, Franco GJ
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ABSTRACTIntroduction: Severe sepsis and septic shock affect millions of people worldwide each year and are responsible for a large number of deaths each year. Hemodynamic deterioration with the development of tissue hypoperfusion, which is the main factor in the development of multiple organ failure and death in consequence. The goal of treatment of septic shock is cardiovascular tissue perfusion and cellular oxygenation safe restoration disoxia avoid. Optimizing shock index during resuscitation may be associated with improvement in systemic tissue perfusion.
Objective: To evaluate the impact of treatment on mortality of septic shock with shock index guidance.
Material and methods: A prospective, randomized, longitudinal patients with septic shock requiring hemodynamic advanced monitoring with pulmonary artery catheter for continuous cardiac output. All variables are optimized shock index hemodynamic guided to a target with a value ‹ 0.9.
Results: A total of 79 patients were included in the study. Baseline characteristics were not significantly different demographic. Were divided into two groups based on the treatment. Group 1: patients with shock index (n = 37) with the optimization of shock index versus Group 2: patients with conventional treatment (n = 42). Mortality for the group resuscitated with shock index was 29.7 versus 66.6% in the conventional group (p ‹ 0.05). Overall mortality was 49.4% similar to that reported in the literature.
Conclusions: The intangible cultural heritage is one of the best ways to evaluate the hemodynamics of the circulatory system and its optimization is associated with improved hemodynamic performance and significantly reduced mortality at 28 days.