Hernández-Del Río JE, Magaña-Cárdenas MT, Hernández-Flores MS

Language: Spanish
References: 12
Page: 152-157
PDF size: 584.17 Kb.

ABSTRACT

Introduction The diabetes mellitus constitutes the most frequent metabolical alteration associated to pregnancy. It is estimated that each year 150,000 newly born from mothers with diabetes. A frequent complication related to these patients is the presence of hypertrophic myocardiopathy; clinically it may present with data of respiratory difficulty, cyanosis and even cardiac failure, depending on the grade of obstruction on the exiting tract of the left ventricle may present sudden death. It is proven that through the optimization on the handling of gestational diabetes, the incidence and severity of this pathology is reduced.
Objective To determine the prevalence of hypertrophic myocardiopathy on children of diabetic mothers and to know the control during the pregnancy when performing HbA1c measuring on newly borns' mothers diagnosed with hypertrophic myocardiopathy.
Material and methods A descriptive cross-sectional study during the period from december 2010 to december 2011 on hopitalized children, either for own causes of maternal. On the services of intensive or medium newly-born care in the area of neonatology of the Fray Antonio Alcalde Civil Hospital of Guadalajara.
Results A total of 36 diabetic mother's children patients, prevalecing on the study the maternal diabetes of gestational type, finding a high grade of complications on these patients that are similar to the data reported on the literature, excepting the respiratory difficulty syndrome with an incidence of 63.8 %. From this sample of patients, 7 of them (19.4%) developed hypertrophic myocardiopathy.
Conclusions There is a clear previously reported association between child and diabetic mother presenting fetal macrosomia and hypertrophic myocardiopathy, finding in this study that when comparing the levels of glycosylated hemoglobin (HbA1c) of the macrosomic patients who did not developed hypertrophic myocardiopathy with the ones who developed it there was a significant correlation between the highest level of HbA1c and the risk of developing hypertrophic myocardiopathy.

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