Arteaga GAC, Castellón PRM

Language: Spanish
References: 6
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Introduction

Cervical intraepithelial neoplasia type 1 infection and human papillomavirus are considered low-grade lesions (LSIL), and refer to atypical cellular changes in the lower third of the epithelium, often accompanied by atypia koilocytotic (effect HPV).
The annual incidence in the United States of CIN I-LSIL is 4%. According to the report of the Secretary of Health cancer screening program in Mexico, in 2011, we identified 1190 cases of cervical cancer, 70.050 of low-grade lesions and high-grade lesions 20.526. (SSA, 2010)
The risk of lesion regression of low degree is 60%, 30% persistence, 10% progression to CIN 3 and the risk of progression to invasive cancer 1% .
There are two types of positions on management for these lesions: immediate treatment vs expectant management. The decision of the type of approach will depend on the cytological findings, colposcopy, cervical biopsy and the characteristics of each patient (age, pregnancy, fertility, etc.).

REFERENCES

1. WHO/ICO information center of hpv and cervical cancer (HPV information center). Human papillomavirus and related cancers in the world. Summary Report 2010.

2. Apgar, et al. Update on ASCCP consensus guidelines for abnormal cervical screening tests and cervical histology. American family physician, 2009.

3. Elit et al. Expectant management versus immediate treatment for low grade cervical intraepithelial neoplasia. Wiley online library, 2011.

4. Pierre et al. Surgery for cervical intraepithelial neoplasia. Cochrane 2009.

5. Burks et al. Risk of CIN 2 among women with a history of previois treatment for cervical intraepithelial neoplasia. Low Genit Tract Dis, 2011.

6. Chummworathay, et al. Cryotherapy for HPV clearance in women with biopsy confirmed cervical low-grade squamous intraepithelial lesions. Int J Gynecol Obst, 2010.