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2013, Number 3

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Med Int Mex 2013; 29 (3)

RS3PE Syndrome in an Elderly as a Paraneoplastic Syndrome of Colon Cancer

Salcido-de Pablo PA, Urrutia- Guerrero JS, Reyes-Cordero GC, Valdés-Castañeda SL, Montiel-Estrada AP, Candia-Zúñiga DI, Bourlón-Cuéllar R, Díaz-Villanueva D
Full text How to cite this article

Language: Spanish
References: 6
Page: 331-334
PDF size: 553.92 Kb.


Key words:

RS3PE, rheumathoid factor, colon cancer.

ABSTRACT

Ninety one years old male with diabetes mellitus, chronic obstructive pulmonary disease, ischemic heart disease, and pancreatic cysts. In March 2012 he presents inflammation and erythema of his left hand. At examination, sinovitis of carpal and distal interphalangeal joints, and pitting edema on left hand dorsum and phalanges. ESR 60 mm/hr (1-7 mm/hr), rheumathoid factor 28.9 U/L (0-20 U/L), ani-cyclic citrullinated peptide ‹16 U (‹20 U), hands radiography with edema of soft tissue, without erosions. Rheumathology diagnoses RS3PE. He presents lower gastrointestinal bleeding, so a colonoscopy is done with biopsy, diagnosing invasor anal sac adenocarcinoma, treated with hemicolectomy and colostomy, with complete resection of the cancer. He is managed with deflazacort, and rehabilitation, with good response.


REFERENCES

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  2. Gurbus DG, Bes C, Guven M, et al. Anti-cyclic citrullinated peptide antibody in patient with Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) accompanied by Gout. Aibu Izzet Baysal tip Dergisi Cilt 2009;4:63-65.

  3. González Naranjo LA. Síndromes reumáticos paraneoplásicos. Iatreia 2011;24:65-75.

  4. Mehmet S. Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) Syndrome and Malignancy. Eur J Gen Med 2004;1:3-5.

  5. Kundu AK. Syndrome of Remitting Seronegative Symmetrical Synovitis with Pitting Oedema (RS3PE). JAPI 2007;55.

  6. Salam A, Henry R, Sheeran T. Acute onset polyarthritis in older people: Is it RS3PE syndrome? Cases Journal 2008; 1:132.1186/1757-1626-1-132




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Med Int Mex. 2013;29