medigraphic.com
SPANISH

Medicina Cutánea Ibero-Latino-Americana

ISSN 0210-5187 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2012, Number 5

<< Back Next >>

Med Cutan Iber Lat Am 2012; 40 (5)

Fibrous hamartoma of infancy

Rosende L, García-Fernández E, Díez E, Perna C, Cuevas J
Full text How to cite this article

Language: Spanish
References: 15
Page: 162-165
PDF size: 111.76 Kb.


Key words:

Fibrous hamartoma, infancy, subcutaneous nodule.

ABSTRACT

Fibrous hamartoma of infancy (HFI) is a rare benign mesenchymal tumor. It is presented as a single subcutaneous tumor in children in the first two years of life. The lesion has a characteristic morphology with a triphasic organoid growth pattern, and the treatment of choice is local excision. We report a case with the distinctive histologic appearance of HFI and cutaneous changes (dilatation of eccrine glands) and a extensive immunohistochemestry study. Finally, differential diagnosis of fibrous tumors of infancy are discussed


REFERENCES

  1. Dickey GE, Sotelo-Avila C. Fibrous hamartoma of infancy: current review. Pediatr Dev Pathol 1999; 2: 236-43.

  2. Yoon TY, Kim JW. Fibrous hamartoma of infancy manifesting as multiple nodules with hypertrichosis. J Dermatol 2006; 33: 427-9.

  3. Enzinger FM. Fibrous hamartoma of infancy. Cancer. 1965; 18: 241-8.

  4. Reye RDK. A consideration of certain subdermal “fibromatous tumours” of infancy. J Pathol Bacteriol 1956; 72: 149-54.

  5. McGowan J 4th, Smith CD, Maize J Jr, Cook J. Giant fibrous hamartoma of infancy: A report of two cases and review of the literature. J Am Acad Dermatol 2011; 64: 579- 86.

  6. Agrawal CS, Agrawal S, Sinha A. Fibrous hamartoma of infancy: a case report. Acta Derm Venereol 2005; 85: 276-7.

  7. Sotelo-Avila C, Bale PM. Subdermal fibrous hamartoma of infancy: pathology of 40 cases and differential diagnosis. Pediatr Pathol 1994; 14: 39-52.

  8. Carretto E, Dall’Igna P, Alaggio R, Siracusa F, Granata C, Ferrari A, Cecchetto G. Fibrous hamartoma of infancy: an Italian multi-institutional experience. J Am Acad Dermatol 2006; 54: 800-3.

  9. Guillou L, Folpe AL. Fibroblastic and fibrohistiocytic tumors: Folpe AL, Inwards CY. Bone and soft tissue pathology (A volume in the series Foundations in Diagnostic Pathology). 1ªed. Philadelphia. Saunders-Elsevier; 2010. pp. 43-96.

  10. Grynspan D, Meir K, Senger C, Ball NJ. Cutaneous changes in fibrous hamartoma of infancy. J Cutan Pathol 2007; 34: 39-43.

  11. Weiss SW, Goldblum JR. Fibrous tumor of infancy and childhood. In: Weiss SW, Goldblum JR. Enzinger and Weiss Soft Tissue Tumors. 5th ed. St. Louis: Mosby Elsevier; 2008. 257-303.

  12. Fetsch JF, Miettinen M, Laskin WB, Michal M, Enzinger FM: A clinicopathologic study of 45 pediatric soft tissue tumors with an admixture of adipose tissue and fibroblastic elements, and a proposal for classification as lipofibromatosis. Am J Surg Pathol 2000, 24: 1491-1500.

  13. Tassano E, Nozza P, Tavella E, Garaventa A, Panarello C, Morerio C. Cytogenetic characterization of a fibrous hamartoma of infancy with complex translocations. Cancer Genet Cytogenet 2010; 201: 66-9.

  14. Lakshminarayanan R, Konia T, Welborn J. Fibrous hamartoma of infancy: a case report with associated cytogenetic findings. Arch Pathol Lab Med 2005; 129: 520-2.

  15. Song YS, Lee IS, Kim HT, Choi KU, Song JW. Fibrous hamartoma of infancy in the hand: unusual location and MR imaging findings. Skeletal Radiol 2010; 39: 1035-8.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Med Cutan Iber Lat Am. 2012;40