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>Journals >Revista Médica del Instituto Mexicano del Seguro Social >Year 2013, Issue 1


Talavera JO, Rivas-Ruiz R
Clinical research XIII. Research design contribution in the structured revision of an article
Rev Med Inst Mex Seguro Soc 2013; 51 (1)

Language: Español
References: 8
Page: 68-72
PDF: 56.36 Kb.


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ABSTRACT

The quality of information obtained in accordance to research design is integrated to the revision structured in relation to the causality model, used in the article “Reduction in the Incidence of Nosocomial Pneumonia Poststroke by Using the ‘Turn-mob’ Program”, which corresponds to a clinical trial design. Points to identify and analyze are ethical issues in order to safeguard the security and respect for patients, randomization that seek to create basal homogeneous groups, subjects with the same probability of receiving any of the maneuvers in comparison, with the same pre maneuver probability of adherence, and which facilitate the blinding of outcome measurement and the distribution between groups of subjects with the same probability of leaving the study for reasons beyond the maneuvers. Other aspects are the relativity of comparison, the blinding of the maneuver, the parallel application of comparative maneuver, early stopping, and analysis according to the degree of adherence. The analysis in accordance with the design is complementary, since it is done based on the architectural model of causality, and the statistical and clinical relevance consideration.


Key words: research design, clinical trial, causality, bias.







>Journals >Revista Médica del Instituto Mexicano del Seguro Social >Year 2013, Issue 1
 

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